慢性化脓性中耳炎手术前、后细菌培养和药敏试验分析

发布时间：2018-05-16 06:33

本文选题：胆脂瘤 + 中耳　；参考：《重庆医学》2014年21期

【摘要】：目的探讨慢性化脓性中耳炎(CSOM)患者在乳突切除手术前、后菌群的动态变化特点。方法收集86例CSOM患者手术前、后的分泌物或组织进行细菌培养和药敏试验,对胆脂瘤组和非胆脂瘤组进行分析。结果 CSOM患者乳突切除术前、术中、术后标本培养阳性率分别为75.6%、41.9%、1.2%;术前细菌阳性、真菌阳性、未检出致病菌在术中培养中分别有49.1%、25.0%、28.6%为细菌阳性;术中胆脂瘤组和非胆脂瘤组的培养阳性率比较差异有统计学意义(P0.05);术中取材中,脓液与组织、乳突鼓窦区与鼓窦入口区组织的细菌培养阳性率比较差异均无统计学意义(P0.05);药敏情况依菌种而异。结论术中培养出的细菌及药敏试验与术前不同,胆脂瘤较非胆脂瘤患者在术中更易培养出细菌,有必要对CSOM患者术前、术中、术后细菌培养和药敏试验进行动态监测。
[Abstract]:Objective to investigate the dynamic changes of microflora in patients with chronic suppurative otitis media (CSOM) before and after mastectomy. Methods bacterial culture and drug sensitivity test were performed in 86 patients with CSOM before and after operation. The cholesteatoma group and non-cholesteatoma group were analyzed. Results before mastoidectomy, the positive rates of culture were 75.61.9and 41.2before mastoid excision, respectively, and the positive rates of bacteria and fungi were 49.1and 25.0and 28.6% respectively in the intraoperative culture of patients with CSOM, and the positive rate of bacteria was 49.1and 25.0and 28.6% respectively before mastoidectomy and before mastoidectomy, and the positive rates of bacteria were 41.9% and 25.0%, respectively. The positive rate of culture in cholesteatoma group and non-cholesteatoma group was significantly higher than that in non-cholesteatoma group (P 0.05). There was no significant difference in the positive rate of bacterial culture between the mastoid tympanic sinus and the inlet of the tympanic sinus, and the drug sensitivity varied with the type of bacteria. Conclusion bacteria and drug sensitivity tests cultured during operation are different from those before operation. Cholesteatoma is easier to culture bacteria than non-cholesteatoma patients during operation. It is necessary to dynamically monitor bacterial culture and drug sensitivity test before, during and after operation in patients with CSOM.
【作者单位】：泸州医学院;重庆市第三人民医院耳鼻咽喉头颈外科;重庆市第三人民医院临床检验中心;
【基金】：重庆医学科研项目资助(2011-1-100)
【分类号】：R764.9

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