银杏叶胶囊辅助治疗VEP异常眼钝挫伤的临床疗效观察

发布时间：2018-05-19 05:05

  本文选题：银杏叶 + 眼钝挫伤　； 参考：《福建中医药大学》2014年硕士论文

【摘要】：目的：通过观察银杏叶胶囊辅助治疗VEP异常眼钝挫伤的临床疗效,评价银杏叶辅助治疗的应用价值。 方法：观察2012年4月至2014年1月在我院就诊的VEP异常的眼钝挫伤患者,共41例(41眼)。随机分为银杏叶组21例(21眼)和对照组20例(20眼),两组予以常规治疗,银杏叶组加用银杏叶胶囊,疗程4周。观察比较两组临床疗效,并对两组治疗前后的最佳矫正视力(BCVA)、视觉诱发电位(VEP)潜伏期值、波幅进行比较。应用SPSS18.0对数据进行统计分析,P0.05为有统计意义。 结果： 1.可比性分析：VEP异常眼钝挫伤患者41例(41眼),其中男性34例(82.93%),女性7例(17.07%)。年龄18-48岁,平均31.22±9.43岁。右眼18例(43.90%),左眼23例(56.10%)。致伤原因：拳头、石头、木棍等撞击伤23例(56.10%),车祸伤7例(17.07%)摔伤6例(14.63%),其他5例(12.20%)；就诊时间：最短时间为外伤后半小时,最长为外伤后2天,半小时至6小时者24例(58.54%),6小时至1天者7例(17.07%),超过1天者10例(24.39%)；就诊时最佳矫正LogMAR视力：光感3眼(7.31%),手动10眼(24.40%),指数5眼(12.20%),3.0-3.9者1眼(2.44%),4.0-4.9者22眼(53.65%),两组患者性别、年龄、就诊时间、就诊时LogMAR视力、潜伏值与波幅经统计学分析差异无统计学意义(P0.05),具有可比性。 2.治疗前视觉诱发电位分组比较：A组：视力≥0.1者,行图形视觉诱发电位检查；B组：视力0.1者,行闪光视觉诱发电位检查。两组患者受伤眼与对侧眼的潜伏期和波幅比较差异有统计学意义(P0.05)。 3.视力比较：两组受伤眼经治疗后LogMAR视力与治疗前比较差异有统计学意义(P0.05)。 4.疗效比较：银杏叶组总有效率(85.71%)优于对照组(75.00%),两者差异具有统计学意义(Z=-2.026,P=0.0430.05)。 5.治疗后P100潜伏期、波幅变化情况比较：银杏叶组治疗后受伤眼与其对侧眼P100潜伏期、波幅比较差异无统计学意义(P0.05),对照组P100潜伏期、波幅比较差异有统计学意义(P0.05)。 结论： 1.眼钝挫伤患者的视觉诱发电位(VEP)检查结果异常,不但明确了视路的损伤,并且能进一步判定其受损的程度。 2.经治疗后两组患者视力较治疗前均有所好转,因此采取及时、有效的治疗,对患者伤后视功能的恢复尤其重要。 3.银杏叶组临床疗效优于对照组,说明银杏叶对加快患者视功能的恢复,起到相辅相成的作用。
[Abstract]:Objective: to observe the clinical effect of ginkgo leaf capsule in the treatment of VEP abnormal ocular contusion and evaluate the application value of ginkgo leaf adjunct therapy. Methods: from April 2012 to January 2014, 41 cases of blunt eye contusion with abnormal VEP were observed. Ginkgo biloba group (21 cases, 21 eyes) and control group (20 cases, 20 eyes) were randomly divided into two groups. The two groups were treated with routine therapy. Ginkgo biloba group was treated with Ginkgo biloba capsule for 4 weeks. To observe and compare the clinical efficacy of the two groups, and to compare the latency and amplitude of BCVAV, VEP before and after treatment. Using SPSS18.0 to carry on the statistical analysis to the data has the statistical significance. Results: 1. The comparative analysis of 41 cases (41 eyes) with abnormal blunt eye contusion of VEP included 34 cases of male (82.933%) and 7 cases of female (7 cases). The average age was 31.22 卤9.43 years. The right eye (n = 18) and left eye (n = 23) were involved in 43.90 and 56.10 respectively. Causes of injury: fist, stone, stick and other impact injuries in 23 cases (56.1010), car accident (7 cases) 17.07) fall in 6 cases (14.63%) and other 5 cases (12.20%) the shortest time of seeing a doctor is half an hour after injury, and the longest time is 2 days after injury. From half hour to 6 hour, 24 cases (58.54 hours, 6 hours to 1 day), 7 cases (17.07%), 10 cases (more than one day) with 24.399.The best corrected LogMAR visual acuity was: light sensation 3 eyes (7.31), manual 10 eyes (24.400), index 5 eyes 12.203.0-3.9 (1 eye) 2.440-4.9 22 eyes 53.650.The two groups had sex, age, time to visit. The visual acuity, latent value and amplitude of LogMAR were comparable. 2. Comparison of visual evoked potentials before treatment in group A: visual acuity 鈮，

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