围术期抗菌药物应用对白内障患者术后感染的影响研究

发布时间：2018-05-21 18:42

本文选题：围术期 + 药物　；参考：《中华医院感染学杂志》2015年23期

【摘要】：目的研究围术期抗菌药物应用对白内障患者术后感染的影响,为白内障手术患者临床合理使用抗菌药物提供有价值的参考。方法将2013年6月-2014年5月医院1 765例患者随机分为局部用药组与联合用药组,局部用药组患者881例,采用局部应用抗菌药物的方法;联合用药组患者884例,采用局部联合全身应用抗菌药物的方法;对比两组患者细菌培养阳性率,术后感染率及应用抗菌药物费用、住院费用。结果局部用药组患者细菌培养阳性124例阳性率14.1%,术后感染2例感染率为0.2%;联合用药组细菌培养阳性126例阳性率14.2%,术后感染2例感染率为0.2%,两组患者培养阳性率与术后感染率比较差异无统计学意义;与联合用药组比较,局部用药组患者的抗菌药物费用和住院费用显著减少、住院时间显著缩短,差异有统计学意义(P0.05)。结论白内障手术患者围术期局部与局部联合全身应用抗菌药物均能够有效预防患者术后感染,但局部用药患者的抗菌药物费用和住院费用显著减少,住院时间显著缩短。
[Abstract]:Objective to study the effect of perioperative antimicrobial application on postoperative infection in cataract patients, and to provide valuable reference for rational use of antibiotics in cataract surgery. Methods from June 2013 to May 2014, 1,765 patients in hospitals were randomly divided into two groups: the local drug group (881 cases) and the combined drug group (884 cases). The positive rate of bacterial culture, the postoperative infection rate, the cost of antimicrobial application and the cost of hospitalization were compared between the two groups. Results the positive rate of bacterial culture was 14.1in the local medication group and 0.2in the postoperative infection group, while the positive rate was 14.2 in the combined drug group and 0.2in the 2 patients with postoperative infection. There was no significant difference in postoperative infection rate. Compared with the combined treatment group, the antimicrobial cost and hospitalization cost in the local drug group were significantly reduced, and the hospitalization time was significantly shortened. The difference was statistically significant (P 0.05). Conclusion Perioperative local and local combined systemic use of antimicrobial agents can effectively prevent postoperative infection, but the cost of antibiotics and hospitalization of local drug patients are significantly reduced, and the hospitalization time is significantly shortened.
【作者单位】：常熟市第二人民医院眼科;
【基金】：江苏省卫生厅基金资助项目(27418312)
【分类号】：R779.66

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