杭州地区680例变应性鼻炎患者常见过敏原检测与分析

发布时间：2018-06-01 02:55

本文选题：变应性鼻炎 + 过敏原　；参考：《中国卫生检验杂志》2014年03期

【摘要】：目的了解杭州地区变应性鼻炎患者常见过敏原分布情况,为临床防治提供一定的依据。方法应用德国Mediwiss敏筛(allergy screen)过敏原免疫印迹定量检测系统对680例变应性鼻炎患者进行血清总IgE和过敏原特异性IgE检测。根据年龄将患者分为儿童组(2~18)岁和成年组(19~82)岁,根据性别分为男性组和女性组。比较各组在过敏原阳性率分布上的差异。结果 680例变应性鼻炎患者患者,总IgE阳性578例(85.00%),其中检测出有特异性IgE阳性489例(71.91%)。阳性率最高的前三位过敏原分别为户尘螨粉尘螨(326例,47.94%)、屋尘(168例,24.71%)和狗毛皮屑(83例,12.21%)。不同性别间,各种过敏原的阳性率差异无统计学意义(P0.05);不同年龄组间,过敏原阳性率差异有统计学意义的有户尘粉尘螨、屋尘、狗毛皮屑、鸡蛋白鸡蛋黄、牛奶、苋和混合霉菌(P0.05)。结论杭州地区变应性鼻炎患者过敏原以螨、屋尘和狗毛皮屑为主,儿童与成人患者在过敏原分布上有所差异。
[Abstract]:Objective to understand the distribution of allergens in patients with allergic rhinitis in Hangzhou, and to provide a certain basis for clinical prevention and treatment. Methods the serum total IgE and allergen specific IgE in 680 patients with allergic rhinitis were detected by the German Mediwiss sensitive screening (allergy screen) allergen immunoblotting system. The children group (2~18) and adult group (19~82) were divided into male and female groups according to sex. The differences in the distribution of the positive rate of allergens were compared. Results 680 patients with allergic rhinitis, total IgE positive in 578 cases (85%), of which 489 cases with specific IgE positive (71.91%) were detected. The highest positive rate of the allergen was the highest. Not as dust mites (326 cases, 47.94%), house dust (168 cases, 24.71%) and dog fur (83 cases, 12.21%). There was no significant difference in the positive rate of allergens between different sexes (P0.05); the positive rates of allergens were statistically significant between the household dust mites, house dust, dog fur, egg white egg yolk, milk, amaranth And mixed mold (P0.05). Conclusion the allergen of allergic rhinitis in Hangzhou area is mainly mite, house dust and dog fur, and the distribution of allergens in children and adult patients is different.
【作者单位】：杭州市第三人民医院;
【分类号】：R765.21

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