鼻咽癌患者术后颅内感染的危险因素分析

发布时间：2018-06-02 01:42

本文选题：鼻咽癌 + 颅内感染　；参考：《中华医院感染学杂志》2014年18期

【摘要】：目的探讨鼻咽癌患者术后发生颅内感染的相关危险因素,为临床防治提供理论依据。方法选择医院2008年12月-2012年12月收治的98例鼻咽癌患者临床病例进行回顾性研究,观察患者发生颅内感染情况,并对发生颅内感染患者与未发生颅内感染患者的临床资料进行对比分析,分析鼻咽癌患者发生颅内感染的相关危险因素。结果 98例鼻咽癌患者发生颅内感染14例,感染率14.29%;经单因素分析发现,患者的年龄、病程、手术入路方式、手术时间、合并疾病、鼻咽癌的病理类型以及肿瘤部位与颅内感染的发生有显著的相关性(P0.05);进一步进行多因素logistic回归分析发现,患者的年龄、病程、手术方式、病理类型以及肿瘤部位是发生颅内感染的独立危险因素。结论导致鼻咽癌患者术后发生颅内感染的因素较多,临床医师需要根据患者的自身情况选择恰当的手术方式,并对相关因素进行针对性干预,以减少感染的发生。
[Abstract]:Objective to investigate the risk factors of intracranial infection in patients with nasopharyngeal carcinoma (NPC) after operation, and to provide theoretical basis for clinical prevention and treatment. Methods A retrospective study of 98 patients with nasopharyngeal carcinoma from December 2008 to December 2012 was conducted to observe the incidence of intracranial infection in patients with nasopharyngeal carcinoma. The clinical data of patients with intracranial infection and those without intracranial infection were compared and analyzed to analyze the risk factors of intracranial infection in patients with nasopharyngeal carcinoma. Results there were 14 cases of intracranial infection in 98 patients with nasopharyngeal carcinoma, and the infection rate was 14.29.The age, course of disease, operative approach, operative time and complicated diseases were found by univariate analysis. There was a significant correlation between the pathological type and tumor location of nasopharyngeal carcinoma and the occurrence of intracranial infection (P 0.05). Pathological type and tumor site are independent risk factors for intracranial infection. Conclusion there are many factors leading to intracranial infection in patients with nasopharyngeal carcinoma after operation. Clinicians should choose the appropriate operation methods according to the patients' own conditions and intervene the relevant factors in order to reduce the incidence of infection.
【作者单位】：山东省临朐县人民医院耳鼻喉科;山东省临朐县人民医院脑外科;
【基金】：山东省科技厅科研基金资助项目(F004372-3)
【分类号】：R739.63

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