Nasopore鼻腔局部联合注射血凝酶在鼻内镜术后止血效果的观察

发布时间：2018-06-06 13:59

本文选题：Nasopore + 注射血凝酶　；参考：《临床耳鼻咽喉头颈外科杂志》2014年08期

【摘要】：目的:采用双盲随机对照临床试验比较功能性鼻内镜术后术腔Nasopore联合注射血凝酶和Nasopore联合生理盐水鼻腔填塞的止血效果。方法:选择确诊为慢性鼻-鼻窦炎需行功能性鼻内镜手术患者68例,随机分为实验组40例和对照组28例。实验组术后给予Nasopore+注射血凝酶填塞(注射血凝酶均使用1U,使用前将其溶解于0.5ml生理盐水中),术毕将溶解有注射血凝酶的生理盐水注入已填入鼻腔的Nasopore中;对照组术后给予纳吸绵填塞,术毕将0.5ml生理盐水注入已填入鼻腔的Nasopore中。通过患者术后VAS评分比较两组在功能性鼻内镜手术后出血效果的差异。结果:对照组术后6h鼻出血VAS评分分别与同组术后1、2、3d比较,差异有统计学意义(P0.05);实验组术后6h的鼻出血VAS评分分别与同时段对照组比较,差异有统计学意义(P0.05)。结论:功能性鼻内镜手术后使用Nasopore作为鼻腔填塞物联合局部使用注射血凝酶,可以有效减少术后6h内的出血。
[Abstract]:Objective: to compare the hemostatic effect of nasal packing with Nasopore and Nasopore in nasal cavity after functional nasal endoscopy in a double-blind randomized controlled clinical trial. Methods: 68 patients with chronic rhinosinusitis were randomly divided into experimental group (n = 40) and control group (n = 28). In the experimental group, Nasopore was injected with hemocoagulase (1U was used for injection of hemagglutinin, then dissolved in 0.5ml saline, then injected with Nasopore in nasal cavity at the end of operation. In the control group, 0.5ml saline was injected into the nasal cavity of Nasopore after operation. Postoperative VAS score was used to compare the bleeding effect between the two groups after functional endoscopic sinus surgery. Results: the VAS score of epistaxis in the control group was significantly higher than that in the control group at 6 hours after operation compared with that in the control group at 1 and 2 days after operation (P 0.05), and the VAS score of epistaxis in the experimental group at 6 hours after operation was significantly higher than that in the control group in the same period (P 0.05). Conclusion: using Nasopore as nasal packing after functional endoscopic sinus surgery combined with local injection of hemocoagulase can effectively reduce bleeding within 6 hours after operation.
【作者单位】：四川大学华西临床医学院
【分类号】：R765.23

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