老年青光眼患者视网膜神经纤维层厚度与视野缺损的相关性

发布时间：2018-06-08 02:37

本文选题：青光眼 + 视网膜神经纤维层厚度　；参考：《中国老年学杂志》2014年19期

【摘要】：目的探讨老年青光眼患者视网膜神经纤维层厚度(RNFL)与视野缺损的相关性。方法将收集到的老年青光眼患者60例(60眼)按照缺损情况分为早中期缺损组(34眼)和重度缺损组(26眼),对两组患者的视野缺损和RNFL厚度进行检测,比较两组之间的差别以及视野缺损和RNFL厚度相关性分析。结果重度视野缺损的RNFL厚度中平均厚度、上方180°厚度、下方180°厚度相应较早中期视野缺损组的低,两组差异显著(P0.05)。重度视野缺损的平均视野缺损、上方半视野、下方半视野缺损的程度相应的都较早中期视野缺损组的程度大(P0.05)。早中期视野缺损组中平均的RNFL厚度与平均视野缺损、上方180°厚度与下方半视野、下方180°厚度与下方半视野均呈现负相关关系(P0.05),重度视野缺损组中平均的RNFL厚度与平均视野缺损、上方180°厚度与下方半视野、下方180°厚度与下方半视野均均无明显的相关关系(P0.05)。结论老年人随着青光眼病情的加重RNFL厚度逐渐降低,视野缺损逐渐的加重,早中期视野缺损患者RNFL厚度与视野缺损呈负相关,晚期青光眼患者RNFL厚度与视野缺损无显著的相关关系。
[Abstract]:Objective to investigate the correlation between retinal nerve fiber layer thickness (RNFL) and visual field defect in elderly patients with glaucoma. Methods 60 cases (60 eyes) of senile glaucoma were divided into early and middle stage defect group (34 eyes) and severe defect group (26 eyes). The visual field defect and RNFL thickness of the two groups were measured. The differences between the two groups and the correlation between visual field defect and RNFL thickness were compared. Results the mean thickness of RNFL in severe visual field defect group was lower than that in early and middle stage visual field defect group. The thickness of RNFL was 180 掳at the top and 180 掳below. The difference between the two groups was significant (P 0.05). The average visual field defect, the upper half visual field and the lower half visual field defect in the severe visual field defect group were higher than those in the early and middle stage visual field defect group (P 0.05). The mean RNFL thickness and mean visual field defect in the early and middle visual field group, the upper 180 掳thickness and the inferior half field, the lower 180 掳thickness and the inferior half visual field were negatively correlated (P 0.05), and the mean RNFL thickness and the average visual field defect in the severe visual field defect group. There was no significant correlation between the upper 180 掳thickness and the inferior half visual field, and between the lower 180 掳thickness and the lower half visual field. Conclusion with the aggravation of glaucoma, the thickness of RNFL is decreasing and the visual field defect is getting worse. The thickness of RNFL is negatively correlated with the defect of visual field in early and middle period. There was no significant correlation between RNFL thickness and visual field defect in patients with advanced glaucoma.
【作者单位】：暨南大学第一附属医院眼科;深圳职业技术学院;
【分类号】：R775

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