阈值期和高危阈值前早产儿视网膜病变临床特点分析

发布时间：2018-06-16 07:30

  本文选题：早产儿视网膜病变 + 阈值病变　； 参考：《第三军医大学学报》2015年12期

【摘要】：目的分析阈值期和高危阈值前早产儿视网膜病变(retinopathy of prematurity,ROP)的临床特点。方法回顾分析2011年1月至2012年12月在北京军区总医院住院治疗确诊的阈值期和高危阈值前ROP患儿106例,分析其出生胎龄、出生体质量、病变程度和病变部位特点。结果 106例阈值期和高危阈值前ROP患儿出生胎龄(28.70±1.89)周。44.34%患儿出生胎龄≤28周,其中2例出生胎龄为24周,2例出生胎龄为25周,84.91%≤30周。出生体质量(1 190.00±282.33)g,86.27%患儿出生体质量1 500 g,20.59%1 000 g,3例患儿出生体质量超过2 000 g。1期病变2.83%,2期21.70%,3期73.58%,4期1.89%,没有5期病变的患儿。33.96%为Ⅰ区病变,66.04%为Ⅱ区病变。Ⅰ区病变患儿的出生胎龄(28.94±1.57)周和出生体质量(1224.31±196.04)g,与Ⅱ区病变患儿[(28.51±2.03)周;1 168.54±321.32)g]无显著性差异(P0.05),治疗时矫正胎龄Ⅰ区病变为(35.09±1.28)周,与Ⅱ区病变(38.43±6.32)周有显著性差异(P=0.000)。结论我国仍有较大、较成熟早产儿进展为阈值期或高危阈值前ROP的情况,目前指南适合我国国情。Ⅰ区病变进展至阈值期或高危阈值前发生较早,应注意及早筛查,缩短筛查间隔,及时治疗。
[Abstract]:Objective to analyze the clinical features of retinopathy of prematural retinopathy (ROP) in premature infants before threshold period and high risk threshold. Methods from January 2011 to December 2012, 106 children with ROP who were diagnosed as threshold period and high risk threshold in Beijing military region General Hospital from January 2011 to December 2012 were analyzed retrospectively. The birth age, body weight, pathological degree and location of ROP were analyzed. Results in 106 patients with ROP, the gestational age was 28.70 卤1.89 weeks. 44.34% of them were aged less than 28 weeks, of which 2 cases were 24 weeks old and 2 cases had 25 weeks of gestational age, 84.91% of them were less than 30 weeks old. Birth weight was 1 190.00 卤282.33 g / g ~ 86.27% (n = 3) > 2 000 g / 1 ~ 2 000 g ~ (-1). The birth weight of 3 cases was above 2 000 g / 1. The body weight was 73.58 and 73.58 ~ (4) stage 1.89, and 66.04% of the children with no stage 5 lesions were area 鈪，

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