视网膜静脉阻塞危险因素的病例对照研究

发布时间：2018-06-24 00:55

本文选题：视网膜中央静脉阻塞 + 视网膜分支静脉阻塞　；参考：《新疆医科大学》2013年硕士论文

【摘要】：目的：探讨近一年内新疆医科大学第一附属医院眼科视网膜静脉阻塞(RVO)患者的人口学特点及其与全身和局部危险因素的关系。方法：采用回顾性病例对照研究。病例组为93例经眼底荧光造影或眼底照相确诊的未接受治疗的RVO初发患者,对照组为86例健康体检者,既往无眼底血管疾病史且年龄、性别、民族构成与病例组大体一致。病例组根据眼底表现类型分为视网膜中央静脉阻塞(CRVO)和视网膜分支静脉阻塞(BRVO)。将各组间全身及眼局部疾病等危险因素用统计学方法比较。结果：RVO是多发于40岁及以上的中老年人的一种严重危害视力的疾病。病例组高血压(OR5.963;95%CI:2.438-14.586)和高密度脂蛋白HDL降低(OR53.167;95%CI:13.277-212.905)的发生率显著高于对照组,而在糖尿病、高胆固醇血症、高甘油三脂血症、低密度脂蛋白高、青光眼、吸烟等方面与对照组无统计学显著差异(p0.05)。CRVO组较BRVO组中男性多、视力差。结论：高血压和血清高密度脂蛋白降低是RVO的独立危险因素,积极诊治全身病对RVO的防治有重要意义。
[Abstract]:Objective: to investigate the demographic characteristics of patients with retinal vein occlusion (RVO) in the first affiliated Hospital of Xinjiang Medical University in recent years and its relationship with systemic and local risk factors. Methods: a retrospective case-control study was conducted. 93 patients with RVO were diagnosed by fundus fluorescein angiography or fundus radiography, and 86 healthy persons in the control group. The patients had no history of fundus vascular disease and had no history of fundus vascular disease. The age, sex, ethnic composition and ethnic composition of the group were roughly the same as those of the case group. The patients were divided into central retinal vein occlusion (CRVO) and retinal branch vein occlusion (BRVO) according to their fundus manifestations. The risk factors of systemic and ocular diseases were compared by statistical method. Results: RVO is a serious vision-threatening disease in the middle-aged and older people over 40 years old. The incidence of hypertension (OR 5.963-95 CI: 2.438-14.586) and decreased HDL (OR53.167 ~ 95CI: 13.277-212.905) in the case group was significantly higher than that in the control group, while in diabetes, hypercholesterolemia, hypertriglyceridemia, high LDL, glaucoma, There was no significant difference in smoking between CRVO group and control group (p0.05). Conclusion: hypertension and decrease of serum high density lipoprotein are independent risk factors of RVO. Active diagnosis and treatment of systemic diseases is of great significance in the prevention and treatment of RVO.
【学位授予单位】：新疆医科大学
【学位级别】：硕士
【学位授予年份】：2013
【分类号】：R774.1

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