不同人工晶状体行后囊后嵌顿术的实验研究

发布时间：2018-06-24 10:31

本文选题：白内障 + 人工晶状体　；参考：《眼科新进展》2014年12期

【摘要】：目的对比3种不同人工晶状体植入术后对幼兔眼前节炎症反应、人工晶状体位置及后囊膜混浊的影响,为儿童后囊后人工晶状体嵌顿术选择合适的人工晶状体。方法 1月龄新西兰白兔36只,随机分成A、B、C 3组,均行右眼晶状体吸出+后囊膜连续环形撕囊联合人工晶状体后囊后嵌顿术,其中A组植入硬片式人工晶状体;B组植入三片式软性人工晶状体;C组植入单片式软性人工晶状体。术后1 d、1周、1个月、3个月分别行术眼的裂隙灯、UBM及眼前节照相检查。结果术后1周时A组的眼前节炎症反应较B组、C组重,差异均有统计学意义(P=0.03、0.03)。术后3个月时A组有2眼人工晶状体夹持,10眼正位;B组11眼正位,1眼偏位;C组2眼正位,8眼偏位,2眼夹持;人工晶状体正位率A组、B组之间差异无统计学意义(P0.05),但与C组间差异均有统计学意义(P=0.03、0.01)。术后3个月时,A组、C组均有2眼出现后囊膜混浊,余术眼后囊膜均保持清亮,后囊膜混浊发生率3组间差异无统计学意义。结论襻为聚丙烯材料、光学部为丙烯酸酯(Acrylic)的三片式人工晶状体更适合儿童后囊后嵌顿术,对维持人工晶状体正位有积极作用。
[Abstract]:Objective to compare the effects of three kinds of intraocular lens implantation (IOL) on inflammatory reaction of anterior segment, position of IOL and posterior capsule opacity in young rabbits, and to select suitable IOL for posterior capsular intraocular lens incarceration in children. Methods Thirty-six 1-month-old New Zealand white rabbits were randomly divided into three groups: right eye lens aspiration, posterior capsular continuous capsulorhexis and posterior intraocular lens posterior capsular incarceration. Group A was implanted with hard intraocular lens and group B was implanted with three pieces of soft intraocular lens and group C was implanted with monolithic soft intraocular lens. Slit-lamp UBM and anterior segment photography were performed 1 week, 1 month and 3 months after operation. Results the inflammatory response of anterior segment in group A was significantly higher than that in group B at 1 week postoperatively (P < 0.03 or 0.03). At 3 months after operation, 2 eyes of group A had intraocular lens clamping (IOL) in 10 eyes. In group B, 11 eyes had positive position and 1 eye had deviation. In group C, 2 eyes had positive position and 8 eyes had deviation. There was no significant difference between group A and group B (P0.05), but there was significant difference between group C and group C (P < 0.030.01). There were 2 eyes of posterior capsule opacification in group A and C at 3 months after operation, but there was no significant difference in the incidence of posterior capsule opacification among three groups. Conclusion Three-slice intraocular lens with polypropylene material and acrylic (Acrylic) as optical part is more suitable for posterior capsular incarceration in children and has a positive effect on maintaining the positive position of intraocular lens.
【作者单位】：安徽医科大学附属省立医院眼科;
【基金】：卫生部“视觉第一中国行动”项目三期(编号:sfca-13-2013-01)~~
【分类号】：R779.6

【参考文献】