下咽癌切除术患者医院感染的危险因素分析

发布时间：2018-06-25 08:11

本文选题：下咽癌切除术 + 术后感染　；参考：《中华医院感染学杂志》2014年09期

【摘要】：目的探讨下咽癌切除术患者术后发生医院感染的危险因素,为临床预防与控制感染提供参考。方法回顾性分析2007年12月-2013年6月耳鼻咽喉科行下咽癌切除手术80例患者的临床资料,找出患者行下咽癌切除术术后发生感染的差异有统计学意义的危险因素,并对危险因素进行非条件logistic回归分析,找出独立危险因素。结果 80例行下咽癌切除手术患者中,11例发生术后感染,感染率为13.75%;经logistic回归分析结果得出,基础疾病(β=0.898,OR=2.542)、抗菌药物使用(β=1.847,OR=5.584)、侵入性操作(β=2.135,OR=7.103)、术前放疗(β=2.007,OR=6.361)、营养不良(β=1.909,OR=5.866)是导致耳鼻咽喉科患者行下咽癌切除术术后发生感染的独立危险因素。结论基础疾病、抗菌药物使用、侵入性操作、术前放疗、营养不良是导致患者行下咽癌切除术后发生感染的独立危险因素,临床上应注意无菌操作,以及术后抗菌药物的合理使用,并加强患者自身免疫力,以降低术后感染率。
[Abstract]:Objective to explore the risk factors of nosocomial infection in patients with hypopharyngeal carcinoma after resection, and to provide reference for clinical prevention and control of infection. Methods from December 2007 to June 2013, the clinical data of 80 patients undergoing resection of hypopharyngeal carcinoma in Otolaryngology were retrospectively analyzed, and the risk factors of infection after hypopharyngeal carcinoma resection were found out. Risk factors were analyzed by non-conditional logistic regression analysis to find out independent risk factors. Results among 80 patients with hypopharyngeal carcinoma resection, 11 cases had postoperative infection, the infection rate was 13.755.The results of logistic regression analysis showed that, Basic diseases (尾 -0.898), antimicrobial use (尾 -1.847OR-5.584), invasive operation (尾 -2.135), preoperative radiotherapy (尾 2.007OR6.361) and malnutrition (尾 1.909OR5.866) were independent risk factors for infection after hypopharyngectomy in patients with otolaryngology. Conclusion basic diseases, antimicrobial use, invasive operation, preoperative radiotherapy and malnutrition are independent risk factors for infection after hypopharyngeal cancer resection. And rational use of postoperative antibiotics, and strengthen the patient's own immunity, in order to reduce postoperative infection rate.
【作者单位】：郑州市人民医院耳鼻咽喉科;
【基金】：河南省杰出人才创新基金资助项目(0621002500)
【分类号】：R739.63

【参考文献】