鼻咽癌腮腺淋巴结转移临床分析
发布时间:2018-06-27 19:30
本文选题:鼻咽肿瘤 + 腮腺/淋巴结 ; 参考:《中国肿瘤临床》2011年02期
【摘要】:目的:探讨鼻咽癌腮腺淋巴结转移的发生概率和表现形式,研究其可能的转移机制及其预后的影响。方法:收集2007年7月至2009年7月江西省肿瘤医院初治鼻咽癌患者MRI诊断考虑有腮腺淋巴结转移者,分析其表现形式,可能的转移机制及预后。结果:2年期间1 004例初治鼻咽癌患者中15例腮腺区结节考虑有淋巴结转移,按拟定诊断标准14例确诊为腮腺淋巴结转移,1例排除,发生率1.4%。转移淋巴结大部分(82%)为浅叶淋巴结。发生腮腺淋巴结转移者绝大部分(93%)为中晚期病例,N_3患者占43%,64%患者有颈部淋巴结包膜外侵,7例患者有Ⅱa及Ⅱb区淋巴结包膜外侵融合。79%的患者有咽旁间隙不同程度侵犯,36%患者放化疗前进行过颈部干预。中位随访10.5个月后,14例患者6例1年内发生远处转移,其中2例已死亡。结论:鼻咽癌腮腺淋巴结转移率为1.4%。其发生可能与颈部淋巴结6cm伴包膜外侵;Ⅱa、Ⅱb区淋巴结融合;咽旁间隙肿瘤占据紧邻腮腺以及既往曾行颈部干预等有关。腮腺淋巴结转移是鼻咽癌预后不良的因素。
[Abstract]:Objective: to investigate the probability and manifestation of parotid lymph node metastasis in nasopharyngeal carcinoma (NPC), and to study the possible metastasis mechanism and its prognostic effect. Methods: MRI diagnosis of nasopharyngeal carcinoma patients with parotid lymph node metastasis was collected from July 2007 to July 2009 in Jiangxi Cancer Hospital. Results: 15 of 1 004 nasopharyngeal carcinoma patients with nasopharyngeal carcinoma had lymph node metastasis in parotid gland. According to the diagnostic criteria, 14 cases were diagnosed as parotid lymph node metastasis, 1 case was excluded, the incidence was 1.4%. Most of the metastatic lymph nodes (82%) were superficial lobular lymph nodes. The majority (93%) of parotid lymph node metastasis were middle or late stage cases. 43 cases (64%) had cervical lymph node extracapsulation, 7 cases (鈪,
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