咽喉反流与发音障碍的相关性研究

发布时间：2018-06-29 09:22

本文选题：咽喉反流 + 反流症状指数量表　；参考：《中国医科大学》2010年硕士论文

【摘要】： 目的通过主客观评估方法分析咽喉反流(laryngopharyngeal reflux, LPR)引起嗓音障碍疾病的嗓音功能特点及对患者生活质量的影响,分析客观评估与主观评估的相关性。方法对112例发音障碍可疑有咽喉反流的患者进行电子鼻咽喉镜检查及反流症状指数量表(the reflux symptom index, RSI)和反流检查计分量表(The reflux finding score, RES)评估,将其中RSI评分13分和(或)RES评分7分定为阳性。两个量表均为阳性诊断为咽喉反流的患者共有50例,对这50例患者进行嗓音障碍指数量表(voice handicap index, VHI)评估及嗓音声学分析及电声门图检查,部分行胃食道镜检查。结果诊断为咽喉反流的50例患者完成问卷调查、VHI评估及嗓音声学分析及电声门图检查,部分接受胃食道镜检查。咽喉反流发音障碍患者的发病与年龄、性别、生活习惯等密切相关。与正常对照组36例志愿者比较,基频、基频微扰、接触率及最大发声时间差异均有统计学意义(P0.01)。VHI量表评估生理P评分最高,其次为功能F评分,情感E评分最低。咽喉反流患者的RFS与VHI有一定相关性(P0.05),而RSI与RFS、VHI无明显相关性(P0.05)。结论咽喉反流造成的声带损伤已经影响到发声功能,主要表现在声带振动不稳定,声门闭合不良,接触时间延长,发声能力下降,对患者的情感方面的影响往往不受患者重视。评估嗓音的客观差异和嗓音对患者生活质量的影响,为咽喉反流疾病的诊断、治疗和预防提供科学依据。在判断治疗效果,随诊动态观察等具有广泛意义,能对患者的依从性产生积极的影响并提高医师对咽喉反流的患者长期治疗的信心。
[Abstract]:Objective to analyze the characteristics of voice function and its influence on the quality of life of patients with voice disorders caused by throat reflux (laryngopharyngeal reflux,) by subjective and objective evaluation, and to analyze the correlation between objective assessment and subjective assessment. Methods one hundred and twelve patients with suspected pharyngeal reflux were evaluated by electronic laryngoscopy and index of reflux symptoms (the reflux symptom index, RSI) and the reflux finding score, res. The RSI score was 13 and / or res score was 7. There were 50 patients with pharynx and larynx reflux diagnosed by the two scales. The voice disturbance index scale (voice handicap index, VHI), voice acoustic analysis and electroglottic examination were performed in 50 patients, and some gastroesophageal examinations were performed. Results 50 patients with pharynx and larynx reflux completed VHI evaluation voice acoustic analysis and electroglottography partly underwent gastroesophageal examination. The incidence of throat reflux dysphonia is closely related to age, sex, life habits and so on. Compared with 36 normal volunteers, the differences of basal frequency perturbation, contact rate and maximal vocal time were statistically significant (P0.01) .VHI scale evaluated physiological P score was the highest, followed by functional F score, emotion E score was the lowest. There was a certain correlation between RFS and VHI in patients with throat reflux (P0.05), but there was no significant correlation between RSI and RFS- VHI (P0.05). Conclusion vocal cord injury caused by pharynx and larynx reflux has affected vocal function, mainly in unstable vocal cord vibration, poor glottis closure, prolonged contact time and decreased vocal ability. Emotional impact on patients is often ignored. Objective differences of voice and influence of voice on patients' quality of life were evaluated to provide scientific basis for diagnosis, treatment and prevention of throat reflux disease. It is of great significance to judge the therapeutic effect and follow up dynamic observation, which can have a positive effect on the compliance of the patients and enhance the doctors' confidence in the long-term treatment of the patients with pharynx and throat reflux.
【学位授予单位】：中国医科大学
【学位级别】：硕士
【学位授予年份】：2010
【分类号】：R767.92

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