鼻腔良恶性肿块的CT和MRI研究

发布时间：2018-06-30 18:18

本文选题：鼻腔 + 肿物　；参考：《暨南大学》2013年硕士论文

【摘要】：目的探讨鼻腔肿块影像学特征及生长方式特点与病变的良恶性的相关性，，旨在提高影像学诊断的准确性。方法搜集2006年1月—2013年1月我院323例鼻腔肿块的CT和/或MRI检查影像资料，所有病历均经手术病理证实。对肿块发生单/双侧别、形态与边缘、骨质改变、生长范围、相邻结构受累情况、上颌旁脂肪层改变、生长方式、肿瘤中心、基底、生长方向、肿瘤密度与信号、强化特点、钙化、坏死/囊变及出血与病灶良恶性的相关性进行分析统计。结果323例鼻腔肿物患者中，良性肿块占233例（72.14%），恶性肿瘤占90例（27.86%）。单因素分析表明肿块的形态、边缘、骨质改变、生长范围、相邻结构受累情况、上颌旁脂肪层改变、生长方式、基底面、生长方向、MRI强化方式及坏死/囊变与病灶的良恶性有相关性（P0.05）。其中骨质破坏和浸润性生长是恶性肿瘤最重要的征象，大多数恶性肿瘤形态不规则，边界不清，基底面不清；肿块超腔生长、上颌窦后方脂肪垫受累和囊变/坏死多见于恶性肿瘤。肿块的发生单/双侧别、肿瘤中心、CT及MRI平扫表现、CT强化方式、CT及MRI强化程度、钙化及出血与病灶的良恶性无明显相关性（P0.05）。结论鼻腔肿块的形态、边缘、骨质破坏、生长范围、相邻结构受累情况、上颌旁脂肪层改变、生长方式、基底、生长方向、MRI强化方式及坏死/囊变可作为判别肿物良恶性的参考指标。
[Abstract]:Objective to investigate the correlation between the imaging features and growth pattern of nasal masses and the benign and malignant lesions in order to improve the accuracy of imaging diagnosis. Methods CT and / or MRI images of 323 cases of nasal masses from January 2006 to January 2013 were collected. All cases were confirmed by operation and pathology. The tumor was characterized by unilateral / bilateral differentiation, morphology and margin, bone change, growth range, involvement of adjacent structures, changes of perimaxillary adipose layer, growth pattern, tumor center, basement, growth direction, tumor density and signal intensity, enhancement characteristics. The correlation of calcification, necrosis / cysts and hemorrhage with benign and malignant lesions was analyzed. Results among 323 cases of nasal masses, 233 cases were benign masses (72.14%), 90 cases were malignant tumors (27.86%). Univariate analysis showed that the shape, margin, bone change, growth range, adjacent structure involvement, perimaxillary fat layer change, growth pattern, basal surface, The pattern of MRI enhancement and necrosis / cysts were correlated with benign and malignant lesions (P0.05). Among them, bone destruction and infiltrative growth are the most important signs of malignant tumor. Most malignant tumors are irregular in shape, unclear in boundary and unclear in basal surface. Posterior maxillary sinus fat pad involvement and cystic / necrotic are more common in malignant tumors. There was no significant correlation between benign and malignant lesions (P 0.05). There was no significant correlation between the enhancement of CT and MRI, calcification and hemorrhage (P0.05). Conclusion the shape, edge, bone destruction, growth range, involvement of adjacent structures, changes of the perimaxillary adipose layer, growth pattern, and basement of the nasal mass were observed. The pattern of MRI enhancement and necrosis / cystic degeneration can be used as a reference index for differentiating benign and malignant tumors.
【学位授予单位】：暨南大学
【学位级别】：硕士
【学位授予年份】：2013
【分类号】：R739.62;R730.4

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