鼻咽癌放疗后患者多层螺旋CT灌注检查感兴趣血管选择的研究

发布时间：2018-07-05 18:53

本文选题：鼻咽癌 + 体层摄影术　；参考：《广西医科大学》2011年硕士论文

【摘要】：目的研究不同感兴趣血管选择对鼻咽癌放疗后局部复发瘤和纤维化灶CT灌注参数的影响,探讨鼻咽癌放疗后患者CT灌注检查时选择替代感兴趣血管的可行性。方法对复发组(19例)和纤维化组(11例)进行CT灌注后,采用颈内动脉-颈内静脉、颈外动脉-下颌后静脉和颈外动脉-颈内静脉作为三对感兴趣血管测量两组的灌注参数,研究其差异性及其对复发瘤的诊断效能。结果采用三组感兴趣血管所得复发组与纤维化组的BF及BV值差异均有统计学意义(P0.05)而MTT及PS值差异均无统计学意义(P0.05)。颈内-颈内组灌注参数BF、BV、MTT、PS的ROC曲线下面积分别为0.909、0.947、0.677、0.703；颈外-下颌后组分别为0.938、0.967、0.648、0.679；颈外-颈内组分别为0.861、0.890、0.641、0.656。三组感兴趣血管所获各灌注值的ROC曲线下面积差异无统计学意义(P0.05)。结论采用上述三组不同感兴趣血管进行CT灌注检查,其BF、BV对鼻咽癌放疗后局部复发瘤及纤维化灶均具有鉴别诊断效能；三组不同感兴趣血管可相互替代完成鼻咽癌放疗后病例的CT灌注检查。
[Abstract]:Objective to study the effect of different interested vessel selection on CT perfusion parameters of local recurrent tumor and fibrosis focus after radiotherapy in nasopharyngeal carcinoma (NPC) patients, and to explore the feasibility of replacing interested vessels in CT perfusion examination of patients with nasopharyngeal carcinoma (NPC) after radiotherapy. Methods after CT perfusion in recurrent group (19 cases) and fibrosis group (11 cases), internal carotid arterial-internal jugular vein, external jugular artery posterior mandibular vein and external jugular artery internal jugular vein were used to measure the perfusion parameters of the two groups. To study its difference and its diagnostic efficacy for recurrent tumors. Results there were significant differences in BF and BV between the recurrent group and fibrosis group (P0.05), but there was no significant difference in MTT and PS (P0.05). The area under the ROC curve of the perfusion parameter BF- BVV / MTT / PS in the intra cervical group was 0.909 / 0.947 / 0.677 / 0.703, respectively, and that in the extracervical / posterior mandibular group was 0.938 / 0.9670.648 / 0.679 and 0.8610.8900.900.641/ 0.641 / 0.656, respectively. There was no significant difference in the area under ROC curve between the three groups (P0.05). Conclusion CT perfusion examination of different interested vessels in the above three groups is effective in differential diagnosis of local recurrent tumors and fibrosis foci after radiotherapy for nasopharyngeal carcinoma. Three groups of different interested blood vessels can substitute each other to complete CT perfusion examination after radiotherapy for nasopharyngeal carcinoma.
【学位授予单位】：广西医科大学
【学位级别】：硕士
【学位授予年份】：2011
【分类号】：R739.63

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