高强度聚焦超声治疗变应性鼻炎疗效观察与分析
发布时间：2018-07-20 08:53
【摘要】： 目的:观察评价高强度超声聚焦疗法对变应性鼻炎的疗效,从流行病学角度分析影响疗效的可能因素,及术后不良反应的发生情况。方法:采用重庆海扶技术有限公司生产地CZB型超声波鼻炎治疗仪对88例变应性鼻炎(Allergy rhinitis, AR)患者行高强度聚焦超声治疗,由1位调查员进行术前及术后随访调查,根据参考文献和临床常见问题设计《HIFU治疗患者调查表》,所有问卷均在调查员指导下完成。结果:88例受试患者中3个月有效人数79人,占总人数89.77%,不同性别患者的HIFU疗效无明显差异,轻度及中-重度组AR在HIFU疗效上存在差异(P0.05),不同年龄及病程的AR病人在HIFU疗效上亦存在不同(P0.05),吸烟作为影响HIFU疗效的危险因素存在,与HIFU疗效存在关联(P0.05,γ=0.239)。鼻腔干燥作为HIFU术后的不良反应症状,可较长时间存在。结论:高强度聚焦超声治疗对病程小于4年的轻度AR患者更具治疗优势;吸烟作为影响HIFU疗效的一个危险因素存在,关联性研究目前仍不确切;HIFU治疗后患者鼻腔干燥症状的存在及缓解情况尚待进一步研究。
[Abstract]:Objective: to observe and evaluate the therapeutic effect of high intensity focused ultrasound therapy on allergic rhinitis and analyze the possible factors affecting the curative effect and the occurrence of postoperative adverse reactions from an epidemiological point of view. Methods: 88 patients with allergic rhinitis (Allergy rhinitis, AR) were treated with CZB ultrasonic rhinitis treatment instrument in Chongqing Haifu Technology Co., Ltd. According to references and clinical frequently asked questions, the questionnaire was designed for HIFU patients. All questionnaires were completed under the guidance of investigators. Results there were 79 effective people in 3 months (89.77%) in 8: 88 subjects. There was no significant difference in the curative effect of HIFU among different sex patients. The curative effect of HIFU was different in mild group and moderate severe group (P0.05), and the curative effect of HIFU was also different in AR patients of different ages and course of disease (P0.05). Smoking, as a risk factor affecting the curative effect of HIFU, was associated with the curative effect of HIFU (P0.05, 纬 0.239). As a symptom of adverse reaction after HIFU, nasal dryness can exist for a long time. Conclusion: high intensity focused ultrasound therapy is more effective in the treatment of mild AR patients whose course is less than 4 years, smoking is a risk factor affecting the curative effect of HIFU. The correlation study is still not exact after HIFU treatment of patients with symptoms of nasal dryness and the situation of relief need to be further studied.
【学位授予单位】：新疆医科大学
【学位级别】：硕士
【学位授予年份】：2010
【分类号】：R765.21
本文编号：2132964
[Abstract]:Objective: to observe and evaluate the therapeutic effect of high intensity focused ultrasound therapy on allergic rhinitis and analyze the possible factors affecting the curative effect and the occurrence of postoperative adverse reactions from an epidemiological point of view. Methods: 88 patients with allergic rhinitis (Allergy rhinitis, AR) were treated with CZB ultrasonic rhinitis treatment instrument in Chongqing Haifu Technology Co., Ltd. According to references and clinical frequently asked questions, the questionnaire was designed for HIFU patients. All questionnaires were completed under the guidance of investigators. Results there were 79 effective people in 3 months (89.77%) in 8: 88 subjects. There was no significant difference in the curative effect of HIFU among different sex patients. The curative effect of HIFU was different in mild group and moderate severe group (P0.05), and the curative effect of HIFU was also different in AR patients of different ages and course of disease (P0.05). Smoking, as a risk factor affecting the curative effect of HIFU, was associated with the curative effect of HIFU (P0.05, 纬 0.239). As a symptom of adverse reaction after HIFU, nasal dryness can exist for a long time. Conclusion: high intensity focused ultrasound therapy is more effective in the treatment of mild AR patients whose course is less than 4 years, smoking is a risk factor affecting the curative effect of HIFU. The correlation study is still not exact after HIFU treatment of patients with symptoms of nasal dryness and the situation of relief need to be further studied.
【学位授予单位】：新疆医科大学
【学位级别】：硕士
【学位授予年份】：2010
【分类号】：R765.21
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