结膜囊内植入物对幼兔眼眶发育的影响

发布时间：2018-07-24 21:27

【摘要】：目的观察眼模置入幼兔结膜囊后刺激眼眶生长发育的程度及引起眶容积的变化。方法选取70只新西兰幼兔(1月龄),随机分为4组,其中A组、B组、C组各20只,均摘除右眼球,保留左眼,A组每隔2周更换1次更大号眼模,B组每隔4周更换1次更大号的眼模,C组不置入眼模;对照组D组10只,不作任何处理。术前和术后12周分别使用CT测双眼眼眶容积。结果术后12周,A组、B组、C组、D组兔右眼眶容积分别为(2.81±0.23)cm3、(2.91±0.19)cm3、(2.57±0.17)cm3和(3.12±0.18)cm3,A组与B组间差异无统计学意义,其余各组间差异均有统计学意义(均为P0.05)。术后12周兔自身左右眼眼眶容积比较,A组、B组、C组差异均有统计学意义(均为P0.05);D组差异无统计学意义(P0.05)。结论结膜囊置入眼模组较不置入眼模组眼眶发育更好,结膜囊置入眼膜能在一定程度上刺激眼眶发育,是促使眶容积增大的有效方法。
[Abstract]:Objective to observe the degree of stimulation of orbital growth and development and the changes of orbital volume after implantation of ocular model into conjunctival sac of young rabbits. Methods 70 New Zealand young rabbits (1 month old) were randomly divided into 4 groups: group A (n = 20), group B (n = 20) and group C (n = 20). The left eye model was changed once every 2 weeks in group A and the larger size was replaced once every 4 weeks in group B, and 10 rats in group D were not placed into the eye model, and 10 in group D were treated without any treatment. The orbital volume was measured by CT before operation and 12 weeks after operation. Results at 12 weeks after operation, there was no significant difference in the volume of right orbit between group A and group B (2.81 卤0.23) cm _ 3, (2.91 卤0.19) cm _ 3, (2.57 卤0.17) cm3 and (3.12 卤0.18) cm _ 3 (P 0.05). 12 weeks after operation, there was no significant difference in orbital volume between group A and group B (P0.05) and group D (P0.05). Conclusion the orbital development in the conjunctival sac implantation group is better than that in the non-implantation model group. The implantation of conjunctival sac can stimulate the orbital development to a certain extent and is an effective method to promote the orbital volume increase.
【作者单位】：云南省第二人民医院眼科;
【基金】：云南省科学技术厅基金(编号:2010ZC223)~~
【分类号】：R779.6

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