青光眼结构与功能的相关性分析

发布时间：2018-07-27 17:37

【摘要】：目的：研究青光眼结构和功能的相关性方法：1.用OCT及标准自动视野计测量开角型青光眼患者27人49眼的视盘面积(DA),视杯面积(CA),盘沿面积(RA),视杯容积(CV)盘沿容积(RV),杯盘面积比(CDR),线性杯盘比(LCDR),视盘竖径(DV),视盘横径(DH)及平均视野缺损(MD),研究其相关性。2.用OCT及标准自动视野计测量开角型青光眼患者21人34眼视盘的视网膜神经纤维层厚度及视野。将代表视网膜神经纤维层厚度的盘沿一周分为12(S1-S12)区,将视野分为21区(Z1-Z21),研究其对应关系。结果：1.视盘参数中以杯盘面积比(CDR)、视杯面积(CA)和线性杯盘比(LCDR)与视野缺损的相关性最大。2.青光眼的视野缺损多首先发生于上下方的旁中心区,即出现弓形暗点；盘沿的丢失多发生于上下极。一侧视野的缺损,则对应相对侧的神经纤维的损害。结论：青光眼的结构和功能具有明显的相关性。这一结论对青光眼的临床早期诊断具有重大意义。
[Abstract]:Objective: to study the correlation between structure and function of glaucoma. Measurement of optic disc area with OCT and standard automatic visual field meter in 49 eyes of 27 patients with open angle glaucoma. (DA), cup area (CA), disc side area (RA), cup volume (RV), disc area ratio (CDR), linear disc area ratio (LCDR), disc vertical diameter (DV), disc transverse area The correlation between diameter (DH) and mean visual field defect (MD),) was studied. 2. 2. Retinal nerve fiber layer thickness and visual field of 34 eyes of 21 patients with open angle glaucoma were measured by OCT and standard automatic visual field. The disc, representing the thickness of retinal nerve fiber layer, was divided into 12 (S1-S12) regions and 21 (Z1-Z21) regions. The result is 1: 1. Among the visual disk parameters, the correlation between the cup area (CA) and the linear cup / disc ratio (LCDR) and the visual field defect was the highest. 2. The ratio of cup to disc area to (CDR), was the highest. The visual field defect of glaucoma occurs first in the central area of the upper and lower sides, that is, there are arcuate dark spots, and the loss of the disc edge occurs mostly in the upper and lower poles. The defect of one side of visual field corresponds to the damage of nerve fiber in the relative side. Conclusion: the structure and function of glaucoma have obvious correlation. This conclusion is of great significance for the early diagnosis of glaucoma.
【学位授予单位】：青岛大学
【学位级别】：硕士
【学位授予年份】：2011
【分类号】：R775

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