中药穴位敷贴对儿童变应性鼻炎IgE及IL-4的影响

发布时间：2018-07-31 13:17

【摘要】：目的:本实验观察中药穴位敷贴对儿童变应性鼻炎IgE及IL-4的影响。方法:按照随机化的原则选择我院门诊符合纳入标准的患儿,分为治疗组及对照组,治疗组在"三伏"和"三九"的第一天选用中药鼻渊灵穴位敷贴治疗,分别为3次,1年共6次,疗程2年,共12次;对照组:用粉尘螨滴剂舌下含服,疗程2年。敷贴前及敷贴1年后、2年后各检测血清IgE、IL-4的水平。结果:IgE水平治疗1年后与治疗前组内比较,治疗组和对照组治疗1年后、2年后与治疗前组内比较,两组有差异(P0.05);两组治疗1年后、2年后组间无差异((P0.05))。IL-4水平治疗组和对照组治疗1年后、2年后与治疗前组内比较,两组有差异(P0.05);两组治疗1年后组间无差异((P0.05));两组治疗2年后组间有差异(P0.05)。结论:中药穴位敷贴能降低变应性鼻炎患儿血清IgE及IL-4水平。
[Abstract]:Objective: to observe the effect of acupoint application of Chinese medicine on IgE and IL-4 in children with allergic rhinitis. Methods: according to the principle of randomization, the outpatients of our hospital were selected and divided into treatment group and control group. The treatment group was treated with Biyuanling acupoint application on the first day of "three volts" and "Sanjiu". There were 3 times, 6 times a year, the course of treatment was 2 years (12 times), and the control group was treated with dust mites drops under tongue for 2 years. The levels of serum IgE IL-4 were measured before and after 1 year and 2 years later. Results after 1 year of treatment, the level of IgE in the treatment group was compared with that in the pre-treatment group, the treatment group and the control group after one year treatment, and two years later compared with the pre-treatment group. There was significant difference between the two groups (P0.05); after 1 year of treatment, there was no difference between the two groups after 2 years of treatment (P0.05). IL-4 levels in treatment group and control group were 1 year after treatment, 2 years after treatment, and 2 years after treatment, the levels of IL-4 in treatment group and control group were compared with those before treatment. There was significant difference between the two groups (P0.05); there was no difference between the two groups after one year of treatment (P0.05) (P0.05) between the two groups after 2 years of); treatment (P0.05). Conclusion: traditional Chinese medicine acupoint application can reduce serum IgE and IL-4 levels in children with allergic rhinitis.
【作者单位】：湖北省中医院儿科;湖北中医药大学;
【基金】：湖北省卫生厅资助项目(编号:2012 Z-Y03)
【分类号】：R276.1

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