眼表烧伤患者结膜囊带菌分析

发布时间：2018-08-03 10:13

【摘要】：目的了解烧伤状态下结膜囊的带菌情况，为其预防性使用抗感染药品提供依据。方法对我院眼表烧伤患者（26只烧伤眼）及自愿者（25只正常眼）的结膜囊进行细菌培养和药物敏感试验，并对其结果进行分析。结果眼表烧伤患者患眼结膜囊细菌阳性率为53.85％（14/26），对照组结膜囊细菌阳性率为56.00%(14/25)，两组比较差异无统计学意义(χ~2=0.024，P=0.877)。烧伤眼（26例）与正常眼（25例）均培养出2个菌种，5个菌株。正常眼所检出的14例阳性菌株中，革兰氏阳性球菌占92.86%，其次为革兰氏阳性杆菌，，占7.14%。阳性菌株中表皮葡萄球菌9株(64.29%)，头状葡萄球菌2株(14.29％)。烧伤眼结膜囊检出的14例阳性菌株，主要由革兰氏阳性球菌构成（92.86%），其次为革兰氏阳性杆菌（占7.14%）。阳性菌株中表皮葡萄球菌6株(42.86%)，溶血葡萄球菌5株(35.74％)。2组结膜囊优势菌种均以表皮葡萄球菌为主。烧伤眼表皮葡萄球菌占总检出阳性菌株的42.86%，较正常组的64.29%低，差异无统计学意义(P=0.449)；烧伤眼溶血性葡萄球菌阳性检出率明显高于正常眼，两组差异有统计学意义(P=0.041)。结论烧伤眼与正常眼结膜囊内的细菌为常居菌。两组细菌阳性检出率、菌种数、革兰分类的构成比无明显差异。但较于正常眼，烧伤眼结膜囊溶血葡萄球菌阳性率明显增高。烧伤患者治疗过程中，应常规进行结膜囊细菌培养，并根据其结果选择敏感抗生素防止感染。
[Abstract]:Objective to investigate the bacterial infection of conjunctival sac under burn condition and to provide evidence for prophylactic use of anti-infective drugs. Methods bacterial culture and drug sensitivity test were carried out in conjunctival sac of 26 burn eyes and 25 normal eyes in our hospital. Results the bacterial positive rate of conjunctival sac was 53.85% (14 / 26) in patients with ocular surface burn and 56.00% (14 / 25) in control group. Two strains and five strains were cultured in burn eyes (26 cases) and normal eyes (25 cases). Among the 14 positive strains detected in normal eyes, Gram positive cocci accounted for 92.86%, followed by Gram-positive bacilli (7.14%). 9 strains (64.29%) were Staphylococcus epidermidis and 2 strains (14.29%) were Staphylococcus cephalis. The 14 positive strains were mainly composed of Gram-positive cocci (92.86%), followed by Gram-positive bacilli (7.14%). Among the positive strains, Staphylococcus epidermidis 6 strains (42.86%), Staphylococcus haemolyticus 5 strains (35.74%) were dominant bacteria in conjunctival sac of group 2, Staphylococcus epidermidis was the dominant bacteria. The positive rate of Staphylococcus epidermidis in burn eyes was 42.86%, which was lower than that in normal group (64.29%), but the positive rate of haemolytic staphylococcus in burn eyes was significantly higher than that in normal eyes (P0. 041). Conclusion bacteria in conjunctival sac of burn eyes and normal eyes are common bacteria. There was no significant difference in the positive rate of bacteria, the number of bacteria and the composition ratio of Gram classification between the two groups. However, the positive rate of staphylococcus conjunctiva hemolysis in burn eyes was significantly higher than that in normal eyes. The bacterial culture of conjunctival sac should be performed regularly during the treatment of burn patients, and sensitive antibiotics should be selected according to the results to prevent infection.
【学位授予单位】：重庆医科大学
【学位级别】：硕士
【学位授予年份】：2013
【分类号】：R779.1

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