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小儿感音神经性听力障碍蜗性病变与蜗后病变ASSR的比较研究

发布时间:2018-08-08 17:09
【摘要】:目的:本研究对小儿重度感音神经性听力障碍蜗性病变和蜗后病变的多频听觉稳态诱发电位(ASSR)各项参数进行对比研究,探讨蜗后病变ASSR存在的一些特异性现象,帮助临床更准确地诊断蜗后听力损害。方法:选取2008-2012年间我院儿童听力中心诊断为"蜗后听觉神经损害"并同时进行了ASSR测试的95例(179耳)患儿作为蜗后病变组;选取同时期诊断为重度及以上"蜗性听觉神经损害"并同时进行了ASSR测试、且与蜗后病变组相同年龄范围的81例(143耳)患儿作为蜗性病变组;选取本儿童听力中心数据库中正常听力并有ASSR测试记录、且与蜗后病变组相同年龄范围者共26例(50耳)作为正常对照组。分别比较上述3组测试对象间ASSR阈值、引出率及ASSR听力图类型的异同。结果:1ASSR阈值:蜗后病变有波Ⅴ有波Ⅰ分化小组各频点的阈值与蜗性病变小组比较,其500、1 000Hz阈值间差异无统计学意义,2 000、4 000 Hz阈值间有统计学差异;蜗后病变无波Ⅴ无波Ⅰ分化小组各频点的阈值均较蜗性病变对应小组500、1 000、2 000、4 000 Hz 4个频点的阈值均有下降。2ASSR引出率:蜗性病变组无波Ⅴ分化者500、1 000、2 000、4 000 Hz各频点的阈值引出率显著性较蜗后病变各小组相对应频率点的引出率为低。3引出ASSR反应频点数量:蜗后病变组能引出全部4个频点ASSR反应的比例显著高于蜗性病变组。4ASSR听力图类型:蜗后病变组的ASSR听力图上升型曲线的比例分别为26.83%(有波Ⅰ波Ⅴ分化)、40%(有波Ⅰ无波Ⅴ分化)和33.80%(无波Ⅰ波Ⅴ分化),远高于蜗性病变组。结论:1临床上ABR重度以上异常的小儿,当ASSR测试出现上升型听力图时,应考虑可能存在蜗后病变的可能;2ASSR反应阈不能用于判断蜗后病变患儿的听力损失严重程度。
[Abstract]:Objective: to compare the (ASSR) parameters of cochlear lesion and retrocochlear lesion in children with severe sensorineural hearing disorder and retrocochlear lesion, and to explore some specific phenomena of ASSR in retrocochlear lesion. To help clinical diagnosis of retrocochlear hearing loss more accurately. Methods: from 2008 to 2012, 95 children (179 ears) who were diagnosed as "retrocochlear auditory nerve damage" by hearing center in our hospital were selected as retrocochlear lesion group. At the same time, 81 cases (143 ears) with severe cochlear auditory nerve damage diagnosed at the same time and with the same age range as retrocochlear lesion group were selected as cochlear lesion group. A total of 26 children (50 ears) with the same age range as the retrocochlear lesion group were selected as the normal control group. The ASSR threshold, the extraction rate and the type of ASSR audiogram were compared among the above three groups. Results 1 ASSR threshold: there was no significant difference in the threshold value of 500-1 000Hz between retrocochlear lesion group and cochlear lesion group (P < 0.05). There was no significant difference between the threshold of 500-1 ASSR and that of cochlear lesion group (P > 0.05). There was no significant difference between the threshold of 500-1 ASSR and that of cochlear lesion group. The threshold value of each frequency of no wave V wave 鈪,

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