鼻部症状对变应性鼻炎患者精神心理的影响

发布时间：2018-08-18 18:16

【摘要】：目的:探讨成人中重度持续性变应性鼻炎(AR)患者在鼻炎发作期的精神心理状态,以及鼻部症状对其精神心理状态的影响。方法:采用症状自评量表(symptom checklist 90,SCL-90)对539例中重度持续性AR患者的精神心理状况进行分析,SCL-90的各因子得分与中国成人正常值即全国常模比较,并统计分析鼻部症状对成人患者的精神心理状态的影响。结果:中重度持续性AR患者的SCL-90得分在躯体化、抑郁、焦虑和敌对4个症状的因子分都明显高于全国常模。男女患者和各年龄组之间各因子分无显著性差异。病程越长躯体化和强迫症状越明显。鼻塞对于躯体化、强迫、人际关系敏感、抑郁、精神病性5个症状具有显著影响;鼻痒对躯体化、抑郁、焦虑3个症状具有显著影响。结论:在鼻炎发作期,中重度持续性AR成人患者的精神心理状态明显比正常中国成人差。鼻塞、鼻痒等鼻部症状明显影响成人中重度持续性AR患者的精神心理状态。临床医生对患者精神心理问题的重视和妥善处理、适当干预将是AR治疗的新趋势。
[Abstract]:Objective: to investigate the mental and psychological status of adult patients with moderate and severe persistent allergic rhinitis (AR) during the attack of rhinitis and the influence of nasal symptoms on their mental and psychological status. Methods: the mental and psychological status of 539 patients with moderate and severe persistent AR were analyzed by symptom Checklist 90 (symptom checklist 90 SCL-90). The scores of SCL-90 were compared with the normal value of Chinese adults, that is, the national norm. The influence of nasal symptoms on mental state of adult patients was analyzed statistically. Results: the factor scores of somatization, depression, anxiety and hostility in moderate and severe persistent AR patients were significantly higher than those in the national norm. There was no significant difference in factor scores between male and female patients and age groups. Somatization and obsessive-compulsive symptoms were more obvious with longer course of disease. Nasal congestion had significant effects on somatization, compulsion, interpersonal sensitivity, depression and psychosis, while nasal itching had significant effects on somatization, depression and anxiety. Conclusion: in the period of rhinitis attack, the mental and psychological state of adult patients with moderate and severe persistent AR is obviously worse than that of normal Chinese adults. Nasal symptoms such as nasal obstruction and itching significantly affect the mental and psychological status of adult patients with moderate and severe persistent AR. It will be a new trend of AR therapy for clinicians to pay attention to patients' mental and psychological problems and properly deal with them.
【作者单位】：首都医科大学附属北京友谊医院耳鼻咽喉头颈外科;耳鼻咽喉科重点实验室(教育部)北京市耳鼻咽喉科研究所;
【基金】：国家自然科学基金杰出青年科学基金(No:81025007) 重点国际合作研究项目(No:81420108009) 国家自然科学青年基金项目(No:81000405) 北京市自然基金(No:7102030) 北京市教委科技计划重点项目(No:KZ200910025008;20110025027)
【分类号】：R765.21

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