不同类型翼状胬肉手术方式的临床对比研究及大样本回顾性统计分析

发布时间：2018-08-19 15:18

【摘要】：目的探索一种复发率低、简易可行的翼状胬肉手术方式,规范翼状胬肉的治疗。方法采用回顾性分析的方法统计中国期刊网近年翼状胬肉不同手术方式的研究结果,研究对象分为6组:单纯切除组、结膜移植组、羊膜移植组、羊膜移植+丝裂霉素C(mitomycin C,MMC)浸润组、角膜缘干细胞(limbal stem cell,LSC)移植组、角膜缘干细胞移植(LSC)+MMC浸润组,同时对临床常用的3种不同手术方式进行临床观察对比研究。所有数据采用SPSS19.0统计软件分析。结果翼状胬肉6种手术方式的复发率总体比较差异有显著统计学意义(χ2=133.260,P0.001),其中单纯切除术(20.00%)、结膜移植术(46.15%)与其他术式间复发率差异均有统计学意义(均为P0.05);羊膜移植术、羊膜移植+MMC术、角膜缘LSC移植术两两组间比较,差异均无统计学意义(均为P0.05);角膜缘LSC移植+MMC术的术后复发率最低(0.36%)。结论角膜缘LSC移植+MMC术是一种复发率低、可进行临床推广治疗翼状胬肉的有效术式。
[Abstract]:Objective To explore a simple and feasible method of pterygium surgery with low recurrence rate and standardize the treatment of pterygium.Methods A retrospective analysis was carried out to analyze the results of different methods of pterygium surgery in recent years. The subjects were divided into six groups: simple excision group, conjunctival transplantation group, amniotic membrane transplantation group, amniotic membrane transplantation + mitosis group. All the data were analyzed by SPSS 19.0 software. Results The recurrence rate of 6 kinds of pterygium surgery was total. There was a significant difference between the two groups (_2 = 133.260, P 0.001). Simple excision (20.00%) and conjunctival transplantation (46.15%) had a significant difference in the recurrence rate between the two groups (all P 0.05); amniotic membrane transplantation, amniotic membrane transplantation + MMC, limbal LSC transplantation had no significant difference between the two groups (all P 0.05). The recurrence rate of limbal LSC transplantation + MMC was the lowest (0.36%). Conclusion Limbal LSC transplantation + MMC is an effective method for pterygium.
【作者单位】：陕西省人民医院眼科;
【基金】：陕西省科技厅社会发展攻关计划项目(编号:2013K12-17-02)~~
【分类号】：R779.6

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