红花注射液治疗突发性聋的疗效及对血清超氧化物歧化酶和丙二醛的影响

发布时间：2018-08-21 07:31

【摘要】：目的:通过分析红花注射液治疗前后突发性聋患者听阈的改变和血清超氧化物歧化酶(SOD)、丙二醛(MDA)的变化,探讨其对突发性聋的治疗机制。方法:40例突发性聋患者随机分为Ⅰ组(红花组)和Ⅱ组(无红花组),检测治疗前后纯音听力、血清MDA、SOD值变化。另选取听力均属于正常范围者25例作为对照组。结果:Ⅰ组治疗总有效率高于Ⅱ组(χ2=4.183,P0.05)。治疗前Ⅰ、Ⅱ组突发性聋患者血清SOD值低于对照组(t值分别为-6.495和-6.945,均P0.05),MDA值高于对照组(t值分别为12.061和10.592,均P0.05)。Ⅰ组治疗后SOD值较治疗前明显增高(t=6.665,P0.05),MDA值较治疗前明显降低(t=-16.497,P0.05)。Ⅱ组治疗后SOD值和MDA值与治疗前比较变化不明显(t值分别为1.556和-0.395,均P0.05)。结论:红花注射液能清除体内的氧自由基,促进听力的恢复。
[Abstract]:Objective: to investigate the mechanism of safflower injection in the treatment of sudden deafness by analyzing the changes of hearing threshold and serum superoxide dismutase (SOD),) malondialdehyde (MDA) in patients with sudden deafness before and after treatment. Methods 40 patients with sudden deafness were randomly divided into two groups: group 鈪，

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