鼻腔鼻窦血管外皮细胞瘤5例临床分析

发布时间：2018-08-23 20:31

【摘要】：目的:提高对鼻腔鼻窦血管外皮细胞瘤的认识和诊治水平。方法:回顾性分析5例鼻腔鼻窦血管外皮细胞瘤患者的临床资料及病理资料。结果:5例CT检查结果提示血管性肿瘤,病变多呈均一高密度块影,并有明显强化的特点。病理检查提示肿瘤富含毛细血管,呈树枝状,管腔内壁为正常内皮细胞,管腔周围有弥漫分布的圆形、卵圆形或梭形外皮细胞排列,可见核分裂像。所有病例均行手术切除并经病理检查证实。肿瘤预后与病理分级密切相关;高度恶性肿瘤的复发率明显高于中间性和低度恶性肿瘤。该组误诊率为80%。结论:血管外皮细胞瘤是一类潜在恶性肿瘤,影像学检查有助于病变的定性定位及手术方案的制定,但缺乏特征性表现,最终诊断需依靠病理学检查。完整手术切除仍是目前最佳的治疗方法。其临床行为与病理分级密切相关,临床医师要重视组织病理学特征的描述。所有病例均需密切随访。
[Abstract]:Objective: to improve the diagnosis and treatment of hemangiopericytoma of nasal cavity and paranasal sinus. Methods: the clinical and pathological data of 5 patients with hemangiopericytoma of nasal cavity and paranasal sinus were retrospectively analyzed. Results the results of CT in 5 cases showed that the lesions of vascular tumors were homogeneous and high density, and had obvious enhancement characteristics. Pathological examination showed that the tumor was rich in capillaries, dendriform, the inner wall of the lumen was normal endothelial cells, there were diffuse round, oval or fusiform outer cells around the lumen, and mitosis was observed. All cases were surgically resected and confirmed by pathology. The recurrence rate of high malignant tumors was significantly higher than that of intermediate and low grade malignant tumors. The misdiagnosis rate of this group was 80. Conclusion: hemangiopericytoma is a kind of potential malignant tumor. The imaging examination is helpful to the qualitative localization of the lesion and the formulation of the surgical plan, but it lacks the characteristic manifestation, and the final diagnosis depends on the pathological examination. Complete surgical resection is still the best treatment at present. Its clinical behavior is closely related to pathological grading. Clinicians should pay attention to the description of histopathological features. All cases should be followed up closely.
【作者单位】：四川省医学科学院四川省人民医院耳鼻咽喉科;
【分类号】：R739.62

【参考文献】