临床耳聋基因诊断实验室构建及管理

发布时间：2018-09-14 21:01

【摘要】：随着分子生物学及转化医学的迅速发展,耳聋基因诊断工作在全国很多地区已经陆续开展,如何构建及管理临床耳聋基因诊断实验室,是保证检测结果准确,减少试验误差的有力保证,本文根据卫计委相关部门出台的相关管理办法及工作导则,结合解放军总医院聋病分子诊断中心实验室的实际临床检测工作,从实验室区域划分、仪器配制、人员配备、检测项目及质量控制五个主要方面和同行交流、探讨临床耳聋基因诊断实验室构建及管理工作。
[Abstract]:With the rapid development of molecular biology and transformational medicine, gene diagnosis of deafness has been carried out in many areas of China. How to construct and manage clinical deafness gene diagnosis laboratory is to ensure the accuracy of the test results. According to the relevant management methods and working guidelines issued by the relevant departments of the Health and Family Planning Commission, and in combination with the actual clinical work of the laboratory of the Molecular diagnosis Center for Deafness in the General Hospital of the PLA, this paper divides the laboratory area into two parts. This paper discusses the construction and management of clinical deafness gene diagnosis laboratory in five main aspects of instrument preparation, staffing, testing items and quality control.
【作者单位】：解放军总医院耳鼻咽喉头颈外科耳鼻咽喉研究所聋病分子诊断中心;解放军总医院海南分院耳鼻咽喉头颈外科;
【基金】：国家十二五支撑项目(2012BAI09B00,2012BAI12B01) 国家自然科学基金重点项目(81230020);国家自然科学基金面上项目(81371096,81371098);国家自然科学基金青年项目(30801285) 卫生部行业专项基金(201202005) 北京市自然科学基金面上项目(7132177,7122172) 北京市科技新星计划(2009B34,2010B081) 国家高技术研究发展计划(“863”,2012AA020101)
【分类号】：R764.43

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