1%环喷托酯—托吡卡混合眼药水与1%阿托品散瞳效果的比较
发布时间：2018-09-19 20:12
【摘要】：目的 对联合散瞳剂(1%环喷托酯滴眼液和1%托吡卡胺滴眼液)在儿童视网膜检影验光中的疗效的观察,及对不良反应的评估。 方法 回顾性分析在我科门诊就诊的140名儿童,280眼,年龄3-15岁,进行裸眼视力、眼外肌功能和交替遮盖试验检查后,再给予联合散瞳剂(1%环喷托酯滴眼液和1%托吡卡胺滴眼液),行视网膜检影验光检查。一周后,受检儿童再复查视网膜检影验光检查(1%硫酸阿托品滴眼液点眼,每日2次,连续1周),把两次验光结果进行对比。3周后,待瞳孔恢复正常,复验最佳矫正视力。还根据验光结果,将弱视眼按严重程度进行分组,并与不同的年龄组进行屈光不正类型及视力损害程度的比较。 结果 受检儿童中弱视眼占21.43%,远视眼占66.43%,正视眼占10.71%,其中低度弱视眼占31.43%,中度弱视眼占37.83%,重度弱视眼占29.29%。联合散瞳剂(1%环喷托酯滴眼液和1%托吡卡胺滴眼液)与1%硫酸阿托品滴眼液验光结果相比少0.43D(t=6.6554,p0.05),有统计学差异,其中弱视眼多0.49D(t=3.9157,p0.05),有统计学差异。在散光值上,两者相比无明显的统计学差异(m=0.06D, t=1.5345, p0.05)。不同年龄组中,屈光不正的程度和类型有统计学差异。通过观察联合散瞳剂的使用,并没有发现不良反应。 结论 虽然联合散瞳剂(1%环喷托酯滴眼液和1%托吡卡胺滴眼液)和1%硫酸阿托品滴眼液在验光结果上存在等效球镜的差异,但它疗效稳定,不良反应少,可广泛用于在读学生的验光检查。
[Abstract]:Objective to observe the efficacy of combined mydriasis (1% cyclopentramate eye drops and 1% topiramine eye drops) in retinal optometry of children and to evaluate the adverse reactions. Methods A retrospective analysis was made on 140 children (280 eyes, aged 3-15 years) who had been examined by naked vision, extraocular muscle function and alternate shading test. Combined mydriasis (1% cyclopentramate eye drops and 1% topiramine eye drops) was given and retinal optometry was performed. One week later, the children were examined with retinal optometry (1% atropine sulfate eye drops, 2 times a day, 1 week in succession). After comparing the results of the two optometry for 3 weeks, the pupil returned to normal and the best corrected visual acuity was re-examined. According to the results of optometry, amblyopia was divided into groups according to severity, and the types of ametropia and the degree of visual impairment were compared with those in different age groups. Results Amblyopia accounted for 21.43, hyperopia accounted for 66.43, positive vision 10.71, low amblyopia 31.43, moderate amblyopia 37.83, and severe amblyopia 29.29, among them, amblyopia was 21.43, hyperopia was 66.43, positive vision was 10.71, and moderate amblyopia was 31.43, moderate amblyopia was 37.83, and severe amblyopia was 29.29. Compared with 1% atropine sulfate eye drops, the optometry results of combined mydriasis (1% cyclopentramate eye drops and 1% topiramine eye drops) were less than 0.43D (t = 6.6554, p0.05), and the amblyopia eyes were more than 0.49D (t 3.9157p0.05). There was no significant difference in astigmatism between the two groups (mA0.06D, tr 1.5345, p0.05). The degree and type of ametropia were statistically different in different age groups. No adverse reactions were found by observing the use of the combined mydriasis. Conclusion although the combined mydriasis (1% cyclopentramate eye drops and 1% topiramine eye drops) and 1% atropine sulfate eye drops have different optometry results, they have a stable curative effect and few adverse reactions. It can be widely used in optometry examination of students.
【学位授予单位】：中南大学
【学位级别】：硕士
【学位授予年份】：2013
【分类号】：R770.4
本文编号：2251208
[Abstract]:Objective to observe the efficacy of combined mydriasis (1% cyclopentramate eye drops and 1% topiramine eye drops) in retinal optometry of children and to evaluate the adverse reactions. Methods A retrospective analysis was made on 140 children (280 eyes, aged 3-15 years) who had been examined by naked vision, extraocular muscle function and alternate shading test. Combined mydriasis (1% cyclopentramate eye drops and 1% topiramine eye drops) was given and retinal optometry was performed. One week later, the children were examined with retinal optometry (1% atropine sulfate eye drops, 2 times a day, 1 week in succession). After comparing the results of the two optometry for 3 weeks, the pupil returned to normal and the best corrected visual acuity was re-examined. According to the results of optometry, amblyopia was divided into groups according to severity, and the types of ametropia and the degree of visual impairment were compared with those in different age groups. Results Amblyopia accounted for 21.43, hyperopia accounted for 66.43, positive vision 10.71, low amblyopia 31.43, moderate amblyopia 37.83, and severe amblyopia 29.29, among them, amblyopia was 21.43, hyperopia was 66.43, positive vision was 10.71, and moderate amblyopia was 31.43, moderate amblyopia was 37.83, and severe amblyopia was 29.29. Compared with 1% atropine sulfate eye drops, the optometry results of combined mydriasis (1% cyclopentramate eye drops and 1% topiramine eye drops) were less than 0.43D (t = 6.6554, p0.05), and the amblyopia eyes were more than 0.49D (t 3.9157p0.05). There was no significant difference in astigmatism between the two groups (mA0.06D, tr 1.5345, p0.05). The degree and type of ametropia were statistically different in different age groups. No adverse reactions were found by observing the use of the combined mydriasis. Conclusion although the combined mydriasis (1% cyclopentramate eye drops and 1% topiramine eye drops) and 1% atropine sulfate eye drops have different optometry results, they have a stable curative effect and few adverse reactions. It can be widely used in optometry examination of students.
【学位授予单位】：中南大学
【学位级别】：硕士
【学位授予年份】：2013
【分类号】：R770.4
【共引文献】
相关硕士学位论文 前2条
1 马鹤;三种睫状肌麻痹剂对儿童调节力及屈光状态的影响[D];中国医科大学;2004年
2 陈玲;远视儿童应用1％环戊通与1％阿托品散瞳验光的对照研究[D];山东大学;2010年
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