病毒性角膜内皮炎的临床分析

发布时间：2018-10-08 08:53

【摘要】：目的：本研究的核心目的是回顾分析26例确诊为病毒性角膜内皮炎患者的临床表现,并发症和复发率。方法：对在2010年9月至2012年12月期间于山东大学齐鲁医院确诊为角膜内皮炎的26例患者,记录其既往史,个人史及临床表现,进行回顾性分析。根据感染灶的形态,将这些病例分为盘状型(I型),弥漫型(II型)和线性类型(III型)。结果：26例患者中有15例男性和11例女性,除2例女性患者分别为9岁和11岁外,其余患者年龄均在35-75岁之间,平均年龄为44.73+16.32岁。这些病例共有的临床表现为眼红,畏光,流泪,视力下降,角膜水肿,KP(++)和睫状充血。此外,有7例(28%)出现眼内压(IOP)升高和继发性青光眼。3例(11.5%)患者分别在治愈后6个月,8个月和4年时复发。结论：角膜内皮炎可导致严重的后果,如继发性青光眼和lOP升高,甚至可致失明,其复发率约为11.5%。因此,对角膜内皮炎病因、治疗及预防的进一步研究亟待展开。
[Abstract]:Objective: to retrospectively analyze the clinical manifestations, complications and recurrence rate of 26 patients with viral corneal endothelitis. Methods: from September 2010 to December 2012, 26 patients with corneal endothelitis diagnosed in Qilu Hospital of Shandong University were analyzed retrospectively. Their past history, personal history and clinical manifestations were recorded and analyzed retrospectively. According to the morphology of the infected foci, these cases were divided into disc type (I type), diffuse type (II type) and linear type (III type). Results there were 15 males and 11 females in the 26 patients. Except for 2 female patients aged 9 and 11, the other patients were between 35 and 75 years old, with an average age of 44.73 16.32 years. The common clinical manifestations of these cases are redness of the eye, photophobia, tears, decreased vision, corneal edema, KP and ciliary hyperemia. In addition, there were 7 cases (28%) with elevated intraocular pressure (IOP) and 3 cases (11.5%) with secondary glaucoma at 6 months, 8 months and 4 years after cure, respectively. Conclusion: corneal endothelitis may lead to severe consequences, such as secondary glaucoma and increased lOP, or even blindness, the recurrence rate is about 11.5%. Therefore, further research on the etiology, treatment and prevention of corneal endothelitis is urgently needed.
【学位授予单位】：山东大学
【学位级别】：硕士
【学位授予年份】：2013
【分类号】：R772.2

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