慢性鼻窦炎、鼻息肉与支气管哮喘相关性194例临床分析
发布时间：2018-10-09 09:31
【摘要】：目的:分析与探讨慢性鼻窦炎、鼻息肉与下呼吸道炎性疾病支气管哮喘、以及其与支气管哮喘肺功能阻塞程度的相关性。方法:对194例慢性鼻窦炎、鼻息肉患者的临床资料进行回顾分析。根据病变范围将慢性鼻窦炎分为单窦、多窦和全鼻窦3种类型;根据鼻内镜检查及CT扫描结果将鼻息肉分成3级;下呼吸道炎性疾病支气管哮喘、以及其与支气管哮喘肺功能阻塞程度分为(小气道阻塞呼吸功能障碍、肺通气阻塞性障碍),同时是否伴发变应性鼻炎。分别对两组患者的肺功能改变程度与疾病的病变范围严重程度进行spearman相关分析检验,以-1r1,P0. 05为有相关性。结果:①慢性鼻窦炎组、慢性鼻窦炎伴息肉组支气管哮喘及变应性鼻炎的发生率比较均无差异无统计学意义(P0.05)②慢性鼻窦炎组72例中29例合并支气管哮喘(单窦、多窦和全鼻窦病变分别为2、19和8例);其中小气道通气功能阻塞患者(单窦、多窦和全鼻窦分别为2、11、6例),肺通气功能阻塞患者(单窦、多窦和全鼻窦分别为0、8、2例)慢性鼻窦炎的病变范围与哮喘患者肺功能(小气道阻塞性通气障碍、肺阻塞性通气功能障碍)呈正相关(0r1,P0.05)。③慢性鼻窦炎伴鼻息肉组122例患者中并发支气管哮喘43例,小气道阻塞性通气障碍Ⅰ-Ⅲ级分别为15、14、3例,肺阻塞性通气功能障碍Ⅰ-Ⅲ级分别为5、5、1例.经统计分析,在不同级别的慢性鼻窦炎伴鼻息肉患者,与哮喘患者肺功能(小气道阻塞性通气障碍、肺阻塞性通气功能障碍)没有相关性。(0r1,P0.05)。④窦口是否阻塞在两组中与患者肺功能阻塞阻塞呼吸功能障碍、肺通气阻塞性障碍呈正相关(0r1,P0.05)。结论:虽然上下呼吸道炎性疾病相关性的机制尚不明确,但慢性鼻窦炎、慢性鼻窦炎伴鼻息肉的疾病病变程度与支气管哮喘肺功能阻塞程度有一定正相关性。
[Abstract]:Objective: to investigate the relationship between chronic sinusitis, nasal polyp and lower respiratory inflammatory diseases, bronchial asthma and pulmonary function obstruction. Methods: the clinical data of 194 patients with chronic sinusitis and nasal polyps were retrospectively analyzed. Chronic sinusitis is divided into three types according to the range of lesions: single sinus, multiple sinuses and total sinuses; nasal polyps are classified into three grades according to the results of nasal endoscopy and CT scan; bronchial asthma, a lower respiratory inflammatory disease, The degree of pulmonary function obstruction in bronchial asthma is divided into two groups: small airway obstruction, respiratory dysfunction, pulmonary ventilation obstructive disorder, and allergic rhinitis at the same time. The degree of pulmonary function change and the severity of disease in two groups were analyzed by spearman correlation test. 05 is related. Results there was no significant difference in the incidence of bronchial asthma and allergic rhinitis between the chronic sinusitis group and the chronic sinusitis with polyp group (P0.05) 2 there were 29 cases of bronchial asthma (single sinus) in the 72 cases of chronic sinusitis group. There were 219 cases with multiple sinuses and 8 cases with total paranasal sinus diseases, among which 6 patients with small airway function obstruction (2116cases with single sinus, 6 patients with multiple sinuses and 6 patients with total paranasal sinuses), patients with pulmonary ventilation dysfunction (monosinus), The pathological range of chronic sinusitis and pulmonary function (small airway obstructive ventilation disorder) in patients with chronic sinusitis were 0% and 82 cases, respectively. There were 43 cases of bronchial asthma in 122 cases of chronic sinusitis with nasal polyps, and 3 cases of small airway obstructive ventilation disorder 鈪，
本文编号：2258852
[Abstract]:Objective: to investigate the relationship between chronic sinusitis, nasal polyp and lower respiratory inflammatory diseases, bronchial asthma and pulmonary function obstruction. Methods: the clinical data of 194 patients with chronic sinusitis and nasal polyps were retrospectively analyzed. Chronic sinusitis is divided into three types according to the range of lesions: single sinus, multiple sinuses and total sinuses; nasal polyps are classified into three grades according to the results of nasal endoscopy and CT scan; bronchial asthma, a lower respiratory inflammatory disease, The degree of pulmonary function obstruction in bronchial asthma is divided into two groups: small airway obstruction, respiratory dysfunction, pulmonary ventilation obstructive disorder, and allergic rhinitis at the same time. The degree of pulmonary function change and the severity of disease in two groups were analyzed by spearman correlation test. 05 is related. Results there was no significant difference in the incidence of bronchial asthma and allergic rhinitis between the chronic sinusitis group and the chronic sinusitis with polyp group (P0.05) 2 there were 29 cases of bronchial asthma (single sinus) in the 72 cases of chronic sinusitis group. There were 219 cases with multiple sinuses and 8 cases with total paranasal sinus diseases, among which 6 patients with small airway function obstruction (2116cases with single sinus, 6 patients with multiple sinuses and 6 patients with total paranasal sinuses), patients with pulmonary ventilation dysfunction (monosinus), The pathological range of chronic sinusitis and pulmonary function (small airway obstructive ventilation disorder) in patients with chronic sinusitis were 0% and 82 cases, respectively. There were 43 cases of bronchial asthma in 122 cases of chronic sinusitis with nasal polyps, and 3 cases of small airway obstructive ventilation disorder 鈪，
本文编号：2258852
本文链接：https://www.wllwen.com/yixuelunwen/yank/2258852.html
最近更新
教材专著
