准分子激光原位角膜磨镶术后视野改变

发布时间：2018-10-09 17:34

【摘要】：目的:探讨准分子激光原位角膜磨镶术(laser in situ keratom ileusis,LASIK)对近视及近视散光患者30°中心视野的影响。方法:将实施LASIK的近视患者45例89眼分为两组:中低度近视组和高度近视组。Ⅰ组:中低度近视组60眼,近视-1.50～-6.00D;Ⅱ组:高度近视组29眼,近视-6.00～10.00D。用Humphrey视野计30-2SITA快速阈值检测程序对所有患者的术前、术后1wk;1,3,6mo的视野进行检查,观察其视野改变情况。观察指标为平均缺损(mean defect,MD)和模式标准差(pattern standard deviation,PSD)。统计学分析采用重复测量的方差分析和非参数分析的秩和检验,分析各时间点视野指数。结果:中低度近视组:术后1wk;1,3mo的MD与术前相比,差异有统计学意义(P0.05),术后6mo时MD值与术前相比差异无统计学意义;PSD值术后各时间点与术前相比差异无统计学意义。高度近视组:术后1wk;1,3mo时的MD均较术前增加,并且随时间变化的差异有统计学意义(P0.05);其中,1wk时MD值上升最明显,以后逐渐下降,但仍高于术前水平;术后6mo时恢复至术前水平(P0.05);术后1wk时的PSD与术前相比差异有统计学意义(P0.05),其余各时间点PSD值与术前相比差异无统计学意义。结论:LASIK手术对高度近视眼患者1wk的视野有影响,对中低度近视患者的视野改变无影响。
[Abstract]:Objective: to investigate the effect of excimer laser in situ keratomileusis (laser in situ keratom ileusis,LASIK) on 30 掳central visual field in myopia and myopic astigmatism. Methods: Forty-five patients (89 eyes) with LASIK were divided into two groups: middle and low myopia group (n = 60) and high myopia group (n = 60), myopia (n = 60) and high myopia group (n = 29). The visual field of all patients was examined before operation and 1 week after operation with Humphrey visual field meter 30-2SITA fast threshold test procedure. The changes of visual field were observed. Mean defect (mean defect,MD) and model standard deviation (pattern standard deviation,PSD) were observed. The visual field index of each time point was analyzed by using the rank sum test of repeated analysis of variance and nonparametric analysis. Results: in the group of moderate and low myopia, there was a significant difference in MD between 1 month and 3 mo after operation (P0.05). There was no significant difference in MD value between postoperation and pre-operation (P0.05). There was no significant difference in MD value between postoperation and pre-operation (P < 0.05). In the group of high myopia, the MD increased at 1wk and 1w ~ 3mo after operation, and the difference with time was statistically significant (P0.05), the MD increased most obviously at 1wk, then decreased gradually, but was still higher than that before operation. The postoperative 6mo returned to the preoperative level (P0.05), the PSD of postoperative 1wk was significantly higher than that of pre-operation (P0.05), and the PSD of other time points had no statistical significance compared with pre-operation. Conclusion the 1wk visual field of the patients with high myopia was affected by the operation of W1 LASIK, but it had no effect on the change of visual field in the patients with moderate and low myopia.
【作者单位】：中国医科大学附属盛京医院眼科;
【分类号】：R779.63

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