突发性聋患者气导短纯音诱发的眼肌前庭诱发肌源性电位

发布时间：2018-10-12 10:30

【摘要】：目的:研究突发性聋患者的眼肌前庭诱发肌源性电位(oVEMP),了解突发性聋患者前庭系统受损范围及程度。方法:选择2013-12-2014-12期间35例诊断为单侧突发性聋的患者。进行气导短纯音诱发的oVEMP检测,计算P1和N1的潜伏期,P1~N1波间期及P1~N1复合波振幅,分别以单侧突发性聋患者的相对健康耳及55例(110耳)健康人对照,分析突发性聋患者椭圆囊及前庭上神经的功能。结果:35例突发性聋患者中,31例双耳均引出oVEMP图形,4例患耳未引出oVEMP图形,患耳引出率88%,95dBHL气导短纯音刺激下31患耳获得P1的潜伏期(12.16±0.76)ms;N1的潜伏期(16.94±2.57)ms,P1~N1波间期(5.16±0.73)ms,P1~N1复合波振幅(2.89±1.66)μv。95dBHL气导短纯音刺激下35健耳获得P1的潜伏期(11.92±0.85)ms;N1的潜伏期(17.07±1.04)ms,P1~N1波间期(5.15±0.69)ms,P1~N1复合波振幅(5.44±2.53)μv;55例健康人均引出典型的oVEMP波形,95dBHL气导短纯音刺激下获得P1的潜伏期(11.53±0.80)ms;N1的潜伏期(16.61±0.87)ms,P1~N1波间期(5.18±1.04)ms,P1~N1复合波振幅(5.96±2.59)μv。突发性聋组患耳、对侧健耳、健康对照组分别进行比较,P1和N1的潜伏期,P1~N1波间期在各组间差异无统计学意义(P0.05)。P1~N1复合波振幅突发性聋组患耳明显低于对侧健耳及健康人,差异有统计学意义(P0.05)。结论:通过oVEMP检测突发性聋患者,可观察到P1~N1复合波振幅降低,可能与椭圆囊及前庭上神经的损害有关。
[Abstract]:Aim: to investigate the extent and extent of vestibular system damage in patients with sudden deafness by (oVEMP),. Methods: 35 patients with unilateral sudden deafness were selected from 2013-12-12-12. The incubation period of P1 and N1, the amplitudes of P1~N1 wave interval and P1~N1 complex wave were calculated, and the relative healthy ears of unilateral sudden deafness patients and 55 healthy people (110 ears) were compared. To analyze the function of elliptical sac and superior vestibular nerve in patients with sudden deafness. Results: of the 35 patients with sudden deafness, 31 had oVEMP patterns in both ears and 4 had no oVEMP patterns in the affected ears. (12.16 卤0.76) ms;N1 latency (16.94 卤2.57) ms,P1~N1 interwave interval (5.16 卤0.73) ms,P1~N1 complex amplitude (2.89 卤1.66) 渭 v.95dBHL short pure tone stimulation 35 healthy ear acquisition P1 latency (11.92 卤0.85) ms;N1 (17.07 卤1.04) ms,P1~N1 interval (5.15 卤0.69) The wave amplitude was (5.44 卤2.53) 渭 v and the typical oVEMP wave was obtained in 55 healthy people. The latency of P1 was obtained by 95dBHL short pure tone stimulation. The latency of P1 was (16.61 卤0.87) ms,P1~N1 interphase and (5.18 卤1.04) ms,P1~N1 complex wave amplitude was (5.96 卤2.59) 渭 v. under the stimulation of 95dBHL short pure tone, the latency of P1 was (11.53 卤0.80) ms;N1. The latency of P1 and N1 and the interval of P1~N1 wave were not significantly different between the two groups (P0.05). The amplitude of P1~N1 complex wave was significantly lower in the affected ears than in the contralateral healthy ears and healthy people. The difference was statistically significant (P0.05). Conclusion: the decrease of the amplitude of P1~N1 complex wave can be observed by oVEMP in patients with sudden deafness, which may be related to the damage of the elliptical sac and the superior vestibular nerve.
【作者单位】：安徽医科大学解放军八一临床学院;解放军第八一医院耳鼻咽喉头颈外科;
【基金】：南京军区十二五科研基金课题MS057资助(No:2011FZ0035)
【分类号】：R764.437

【参考文献】