难治性弱视眼视网膜厚度分析
发布时间：2018-10-16 22:21
【摘要】：目的利用光学相干断层扫描技术(OCT)检测难治性弱视眼的视网膜厚度,探讨难治性弱视是否存在视网膜形态学改变,为其发病机制的研究提供一定的理论依据。 方法从青岛大学医学院附属医院眼科2010年5月-2011年4月门诊就诊的弱视患儿中选择难治性弱视眼27例30眼作为实验组,另选非难治性弱视眼22例30眼、屈光度±1.00D的同龄正常儿19例30眼作为对照组。用光学相干断层扫描仪(Opti cal Coherence Tomography OCT)对实验组和对照组患儿的黄斑区进行快速扫描,测量黄斑中心凹、中心区(1mm直径范围)及旁中心区(直径为3mm环形区域内)上方、下方、鼻侧、颞侧的平均视网膜厚度,比较不同区域视网膜厚度的差别。 结果难治性弱视眼、非难治性弱视眼、正常对照眼黄斑中心凹厚度分别为198.83±32.33μm、189.57±29.59μm和178.10±29.29μm,三组比较差异均有统计学意义(P值分别为0.03、0.004、0.001,(P0.05)。难治性弱视眼、非难治性弱视眼、正常对照眼黄斑中心区平均厚度分别为225.47±19.85μm、219.93±18.55μm和213.47±28.33μm,三组比较,P值分别为P=0.03、0.045、0.001,差异也均有统计学意义(P0.05)。而黄斑旁中心区上方、下方、鼻侧及颞侧视网膜厚度,难治性弱视眼分别为298.70±27.71μm、298.63±26.36μm、298.00±31.5μm、292.27±30.04μm,非难治性弱视眼分别为300.10±25.46μm、297.33±31.04μm、298.33±34.23μm、286.57±24.87μm,正常对照眼分别为297.07±23.28μm、294.57±39.27μm、299.07±24.48μm、294.57±39.27μm,四象限区域视网膜厚度在三组之间,差异均无明显统计学意义(P0.05)。 结论难治性弱视眼黄斑中心凹、中心区视网膜厚度增加,黄斑旁中心区上方、下方、鼻侧及颞侧视网膜厚度无明显改变。
[Abstract]:Objective to detect the retinal thickness of refractory amblyopia by optical coherence tomography (OCT), and to investigate whether there are retinal morphological changes in refractory amblyopia, so as to provide a theoretical basis for the study of the pathogenesis of refractory amblyopia. Methods from May 2010 to April 2011, 27 cases (30 eyes) of refractory amblyopia and 22 cases (30 eyes) of non-refractory amblyopia were selected as experimental group. The diopter 卤1.00D of 19 normal infants of the same age was 30 eyes as the control group. The macular area of the experimental group and the control group was scanned by optical coherence tomography (Opti cal Coherence Tomography OCT). The macular fovea, the central area (1mm diameter range) and the paracentral area (diameter of 3mm ring area) were measured. The mean retinal thickness of nasal side and temporal side was compared between different regions. Results the thickness of fovea of macula in refractory amblyopia, non-refractory amblyopia and normal control eyes was 198.83 卤32.33 渭 m, 189.57 卤29.59 渭 m and 178.10 卤29.29 渭 m, respectively. The difference among the three groups was statistically significant (P < 0.05). The mean macular central area thickness of refractory amblyopia eyes, non-refractory amblyopia eyes and normal control eyes were 225.47 卤19.85 渭 m, 219.93 卤18.55 渭 m and 213.47 卤28.33 渭 m, respectively (P < 0.05). 鑰岄粍鏂戞梺涓績鍖轰笂鏂，
本文编号：2275805
[Abstract]:Objective to detect the retinal thickness of refractory amblyopia by optical coherence tomography (OCT), and to investigate whether there are retinal morphological changes in refractory amblyopia, so as to provide a theoretical basis for the study of the pathogenesis of refractory amblyopia. Methods from May 2010 to April 2011, 27 cases (30 eyes) of refractory amblyopia and 22 cases (30 eyes) of non-refractory amblyopia were selected as experimental group. The diopter 卤1.00D of 19 normal infants of the same age was 30 eyes as the control group. The macular area of the experimental group and the control group was scanned by optical coherence tomography (Opti cal Coherence Tomography OCT). The macular fovea, the central area (1mm diameter range) and the paracentral area (diameter of 3mm ring area) were measured. The mean retinal thickness of nasal side and temporal side was compared between different regions. Results the thickness of fovea of macula in refractory amblyopia, non-refractory amblyopia and normal control eyes was 198.83 卤32.33 渭 m, 189.57 卤29.59 渭 m and 178.10 卤29.29 渭 m, respectively. The difference among the three groups was statistically significant (P < 0.05). The mean macular central area thickness of refractory amblyopia eyes, non-refractory amblyopia eyes and normal control eyes were 225.47 卤19.85 渭 m, 219.93 卤18.55 渭 m and 213.47 卤28.33 渭 m, respectively (P < 0.05). 鑰岄粍鏂戞梺涓績鍖轰笂鏂，
本文编号：2275805
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