IOLMaster在某些特殊眼中的临床应用
发布时间：2018-11-17 09:34
【摘要】： 目的： 1.对比分析IOLMaster和接触式A超两种生物测量方法测算伴后巩膜葡萄肿的高度近视白内障患者IOL度数的精确性,比较不同IOL计算公式的准确性。 2.对比分析IOLMaster和接触式A超测得的黄斑水肿患者的眼轴长度(axial length,AL),探讨眼轴测量差值与黄斑中心凹厚度的相关性。 3.评价IOLMaster测量硅油眼AL的精确性。 方法： 1.本研究为前瞻性病例对照临床研究。 2.收集伴后巩膜葡萄肿的高度近视白内障患者28例(41眼),所有患者均行白内障超声乳化联合IOL植入术,术前分别用IOLMaster和接触式A超联合手动角膜曲率计(manual keratometer,MK)测量生物参数；并根据SRK-II,SRK-T,Haigis,Hoffer Q,Holladay 1公式计算IOL度数；术后3个月检查患者屈光状态。 3.收集确诊为黄斑水肿的患者42例(67眼),正常对照组30例(40眼)。应用TOPCON 3D OCT-1000测得病例组及对照组黄斑中心凹厚度,并应用IOLMaster和接触式A超测量患者的AL。 4.收集在本院行玻璃体切割联合硅油填充术的患者26例(30眼),分别于术前1天和术后1个月应用IOLMaster测量AL,观察前后有无差异。 5.统计学方法：本研究使用SPSS16.0统计学软件,两种方法的比较应用配对设计资料的t检验、单因素方差分析；不同IOL计算公式间率的比较应用配对设计下两组频数分布χ2检验(又称McNemar检验)；应用Pearson相关系数进行相关性分析。 结果： 1.IOLMaster和接触式A超测得的AL和前房深度差异均有统计学意义(P=0.005,0.000);IOLMaster与MK测得的角膜曲率差异无统计学意义(P=0.398)。MAE以±1.00D为界做χ2检验,只有应用Haigis公式时IOLMaster与接触式A超差异有统计学意义(χ2=3.953,P=0.047)。应用IOLMaster生物测量方法,SRK/T,Haigis公式最精确,应用接触式A超联合MK生物测量方法Holladay 1,Hoffer Q,Haigis公式最精确,平均绝对屈光误差(mean absolute refractive error,MAE)较为接近。 2.黄斑水肿患者的平均黄斑中心凹厚度为(377.85±119.84)μm;IOLMaster和接触式A超测得的AL分别为(22.95±0.97)mm和(22.82±1.04)mm,差异有统计学意义(P=0.003)；但AL差值与OCT测得的黄斑中心凹厚度无相关性(r=-0.097：P=0.447)。 3.应用IOLMaster在有、无硅油填充时测得的AL分别是(24.38±3.18)mm和(24.23±2.91)mm,非参数检验差异无统计学意义(P=0.261)。 结论： 1.对于伴后巩膜葡萄肿的高度近视白内障患者,只有应用Haigis公式时IOLMaster测算的IOL度数较接触式A超精确；应用IOLMaster生物测量方法推荐使用SRK/T,Haigis公式；应用接触式A超联合MK生物测量方法推荐使用Holladay 1,Hoffer Q,Haigis公式。 2.IOLMaster接触式A超所测得的黄斑水肿患者的AL差异有统计学意义,但是其差值与黄斑中心凹厚度无相关性。 3.有、无硅油填充对IOLMaster测量眼轴没有影响。
[Abstract]:Objective: 1. To compare and analyze the accuracy of IOLMaster and contact A-ultrasound in estimating the IOL degree of high myopic cataract patients with posterior scleral grape swelling, and to compare the accuracy of different IOL calculation formulas. 2. The eye axis length (axial length,AL) of patients with macular edema measured by IOLMaster and contact A ultrasound was compared and analyzed to explore the correlation between the difference of eye axis and the thickness of macular fovea. 3. To evaluate the accuracy of IOLMaster in measuring AL of silicone eye. Methods: 1. This study is a prospective case-control clinical study. 2. Twenty-eight cases (41 eyes) of high myopia cataract with posterior scleral grape swelling were collected. All patients were treated with phacoemulsification combined with IOL implantation. IOLMaster and contact A ultrasound combined with manual keratometer (manual keratometer, were used before operation. MK) was used to measure biological parameters. The degree of IOL was calculated according to the formula of SRK-II,SRK-T,Haigis,Hoffer QG Holladay 1, and the refractive state of the patients was examined 3 months after operation. 3. 42 cases (67 eyes) of macular edema and 30 cases (40 eyes) of normal control group were collected. The thickness of macular fovea was measured by TOPCON 3D OCT-1000 in case group and control group. IOLMaster and contact A ultrasound were used to measure AL. in patients. 4. A total of 26 patients (30 eyes) who underwent vitrectomy combined with silicone oil implantation in our hospital were collected. IOLMaster was used to measure AL, 1 day before operation and 1 month after operation. 5. Statistical methods: SPSS16.0 software was used to compare the two methods with t-test of paired design data, and single factor analysis of variance (ANOVA). Comparison of the rates of different IOL formulas two groups of frequency distribution 蠂 2 test (also called McNemar test) and Pearson correlation coefficient were used to analyze the correlation between the two groups. Results: there was significant difference between AL and anterior chamber depth measured by 1.IOLMaster and contact A ultrasound (P0. 005U 0. 000). There was no significant difference in corneal curvature between IOLMaster and MK (P < 0. 398). MAE 卤1. 00D was used as 蠂 2 test). Only when the Haigis formula was used, there was a significant difference between IOLMaster and contact A ultrasound (蠂 2 + 3. 953% P 0. 047). Using IOLMaster biometric method, SRK/T,Haigis formula is the most accurate, and contact A-super combined with MK biometric method Holladay 1Hoffer QI Haigis formula is the most accurate, and the average absolute refractive error (mean absolute refractive error,MAE) is close. 2. The mean foveal thickness of macular fovea in patients with macular edema was (377.85 卤119.84) 渭 m IOLMaster and (22.95 卤0.97) mm and (22.82 卤1.04) mm, respectively (P0. 003). However, there was no correlation between AL difference and macular foveal thickness measured by OCT (r=-0.097:P=0.447). 3. The AL measured by IOLMaster was (24.38 卤3.18) mm and (24.23 卤2.91) mm, respectively. Conclusion: 1. For high myopic cataract patients with posterior scleral grape swelling, the IOL degree calculated by IOLMaster with Haigis formula is more accurate than that of contact A, and SRK/T,Haigis formula is recommended by IOLMaster biometrics. In this paper, we recommend the use of Holladay 1 / Hoffer QS Haigis formula by means of contact A ultrasound combined with MK biometrics. There was significant difference in AL between the patients with macular edema measured by 2.IOLMaster contact A ultrasound, but there was no correlation between the difference and the foveal thickness of macular. 3. Yes, no silicone oil filling has no effect on the IOLMaster measurement eye shaft.
【学位授予单位】：天津医科大学
【学位级别】：硕士
【学位授予年份】：2010
【分类号】：R77
本文编号：2337305
[Abstract]:Objective: 1. To compare and analyze the accuracy of IOLMaster and contact A-ultrasound in estimating the IOL degree of high myopic cataract patients with posterior scleral grape swelling, and to compare the accuracy of different IOL calculation formulas. 2. The eye axis length (axial length,AL) of patients with macular edema measured by IOLMaster and contact A ultrasound was compared and analyzed to explore the correlation between the difference of eye axis and the thickness of macular fovea. 3. To evaluate the accuracy of IOLMaster in measuring AL of silicone eye. Methods: 1. This study is a prospective case-control clinical study. 2. Twenty-eight cases (41 eyes) of high myopia cataract with posterior scleral grape swelling were collected. All patients were treated with phacoemulsification combined with IOL implantation. IOLMaster and contact A ultrasound combined with manual keratometer (manual keratometer, were used before operation. MK) was used to measure biological parameters. The degree of IOL was calculated according to the formula of SRK-II,SRK-T,Haigis,Hoffer QG Holladay 1, and the refractive state of the patients was examined 3 months after operation. 3. 42 cases (67 eyes) of macular edema and 30 cases (40 eyes) of normal control group were collected. The thickness of macular fovea was measured by TOPCON 3D OCT-1000 in case group and control group. IOLMaster and contact A ultrasound were used to measure AL. in patients. 4. A total of 26 patients (30 eyes) who underwent vitrectomy combined with silicone oil implantation in our hospital were collected. IOLMaster was used to measure AL, 1 day before operation and 1 month after operation. 5. Statistical methods: SPSS16.0 software was used to compare the two methods with t-test of paired design data, and single factor analysis of variance (ANOVA). Comparison of the rates of different IOL formulas two groups of frequency distribution 蠂 2 test (also called McNemar test) and Pearson correlation coefficient were used to analyze the correlation between the two groups. Results: there was significant difference between AL and anterior chamber depth measured by 1.IOLMaster and contact A ultrasound (P0. 005U 0. 000). There was no significant difference in corneal curvature between IOLMaster and MK (P < 0. 398). MAE 卤1. 00D was used as 蠂 2 test). Only when the Haigis formula was used, there was a significant difference between IOLMaster and contact A ultrasound (蠂 2 + 3. 953% P 0. 047). Using IOLMaster biometric method, SRK/T,Haigis formula is the most accurate, and contact A-super combined with MK biometric method Holladay 1Hoffer QI Haigis formula is the most accurate, and the average absolute refractive error (mean absolute refractive error,MAE) is close. 2. The mean foveal thickness of macular fovea in patients with macular edema was (377.85 卤119.84) 渭 m IOLMaster and (22.95 卤0.97) mm and (22.82 卤1.04) mm, respectively (P0. 003). However, there was no correlation between AL difference and macular foveal thickness measured by OCT (r=-0.097:P=0.447). 3. The AL measured by IOLMaster was (24.38 卤3.18) mm and (24.23 卤2.91) mm, respectively. Conclusion: 1. For high myopic cataract patients with posterior scleral grape swelling, the IOL degree calculated by IOLMaster with Haigis formula is more accurate than that of contact A, and SRK/T,Haigis formula is recommended by IOLMaster biometrics. In this paper, we recommend the use of Holladay 1 / Hoffer QS Haigis formula by means of contact A ultrasound combined with MK biometrics. There was significant difference in AL between the patients with macular edema measured by 2.IOLMaster contact A ultrasound, but there was no correlation between the difference and the foveal thickness of macular. 3. Yes, no silicone oil filling has no effect on the IOLMaster measurement eye shaft.
【学位授予单位】：天津医科大学
【学位级别】：硕士
【学位授予年份】：2010
【分类号】：R77
【参考文献】
相关期刊论文 前9条
1 李新宇;刘磊;袁菁;董洁玉;邹艳;;不同角膜曲率测量方法结果的比较[J];国际眼科杂志;2006年03期
2 应良,姚瞻,马楠,韩冬生,周增超,王瑶;A、B超联合法测眼轴在高度近视眼人工晶状体度数计算中的应用[J];临床眼科杂志;2002年06期
3 史桂桃;艾育德;;超声检查在眼科的临床应用[J];内蒙古医学杂志;2006年12期
4 姜燕;施玉英;杨文利;;六种人工晶状体屈光度数计算公式的准确性比较[J];眼科;2007年02期
5 宋学东,杨军,计建军,王延群;眼部生物测量的准确性分析[J];眼科研究;1997年04期
6 陈卉;;Bland-Altman分析在临床测量方法一致性评价中的应用[J];中国卫生统计;2007年03期
7 莫小庆;眼轴长度与人工晶体屈光度测算[J];镇江医学院学报;1999年02期
8 戴锦晖,褚仁远,陆国生;高度轴性近视眼白内障手术屈光误差分析[J];中国实用眼科杂志;1999年10期
9 郑丹莹,张振平,杨文辉,杨晖,郭未艾,胡蓉;光学相干生物测量仪测量人工晶体度数的初步研究[J];中国实用眼科杂志;2002年06期
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