大环内脂类药物联合糖皮质激素治疗无局部解剖结构异常的慢性鼻-鼻窦炎

发布时间：2018-11-20 05:48

【摘要】：正慢性鼻炎是鼻黏膜及黏膜下层的慢性炎症,慢性鼻窦炎为鼻窦的慢性化脓性炎症,慢性鼻炎与鼻窦炎同时存在称为慢性鼻-鼻窦炎(CRS),CRS是涉及鼻腔和一个或多个鼻窦黏膜的炎性病变,疾病的病因病机复杂,变态反应、免疫缺陷等系统性宿主因素、甲泡、中鼻甲反向弯曲等局部性宿主因素和病原微生物、有害化学物等环境因素等均可导致CRS的发生。《慢性鼻-鼻窦炎诊断和治疗指南》指出CRS治疗首选方案为药物治疗,CRS治疗主要目标为抗炎,大环内酯类药物为首选推荐抗
[Abstract]:Positive chronic rhinitis is the chronic inflammation of nasal mucosa and submucosa. Chronic sinusitis is chronic suppurative inflammation of nasal sinuses. Chronic rhinitis and sinusitis coexist with chronic rhinosinusitis (CRS),. CRS is an inflammatory disease involving nasal cavity and one or more nasal mucosa. The etiology and pathogenesis of the disease are complicated, allergic reaction, immune deficiency and other systemic host factors, local host factors and pathogenic microbes, such as thyroid follicle, reverse curvature of middle turbinate, etc. Environmental factors such as harmful chemicals can lead to the occurrence of CRS. The guidelines for the diagnosis and treatment of chronic rhinosinusitis point out that the first choice of CRS treatment is drug therapy, the main goal of CRS treatment is anti-inflammatory, and macrolides are the first recommended anti-inflammatory drugs.
【作者单位】： 辽宁医学院附属第一医院耳鼻咽喉科;
【分类号】：R765.41
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本文编号：2343959