第二个孤立的视网膜动脉在视网膜分支静脉阻塞中的作用

发布时间：2018-11-20 17:48

【摘要】： 目的：视网膜分支静脉阻塞(BRVO)是最常见的视网膜血管性疾病之一。通常发生在伴有高血压,动脉硬化,糖尿病及血液粘稠等系统性疾病的老年人。视网膜分支静脉阻塞的发病机制是多因素参与的病理生理过程,目前尚未完全阐明。其中“第二个孤立的视网膜动脉”在视网膜分支静脉阻塞(BRVO)中的作用很少有文献报道。本研究评价了“第二个孤立的视网膜动脉”在视网膜分支静脉阻塞中的作用。方法：随机抽取2008年3月至2009年10月在大连医科大学附属第一医院眼科诊治的130例患者(260只眼),其中BRVO眼65例(130只眼),其他非血管性眼底病65例(130只眼)。分别对其进行彩色眼底照相及荧光血管造影(FFA)检查并分组。BRVO眼65只眼为组1,其对侧眼(健眼)65只眼为组2,其他非血管性眼底病130只眼为组3。将组1的65只BRVO眼,按有和无“第二个孤立的视网膜动脉”分为a组和b组。对各组存在的“第二个孤立的视网膜动脉”进行记录。并对a组和b组的初诊及随诊1周、1个月、3个月及6个月视力分别进行记录,并分别进行统计学分析。结果：1, BRVO眼(8／65,12%)与对侧眼(14／65,22%)相比,存在“第二个孤立的视网膜动脉”的数目差异没有统计学意义,χ2=1.96(P 0.05); BRVO眼(8／65,12%)与其他非血管性眼底病组眼(44／130,34%)相比,存在“第二个孤立的视网膜动脉”的数目差异有统计学意义χ2=10.23(P0.05)。2,在BRVO眼组中有和无“第二个孤立的视网膜动脉”(即a组与b组)的初诊视力差异有统计学意义(P0.05)。随诊1周、1个月、3个月及6个月的视力也分别比较,差异均具有统计学意义(P0.05)。结论：“第二个孤立的视网膜动脉”,可能降低视网膜动静脉交叉的数目而降低BRVO的发病,并间接提高BRVO眼初诊视力,而对BRVO眼视力预后具有保护作用。
[Abstract]:Objective: (BRVO) is one of the most common retinal vascular diseases. It usually occurs in the elderly with systemic diseases such as hypertension, atherosclerosis, diabetes, and blood viscosity. The pathogenesis of retinal branch vein occlusion (RVO) is a multifactor pathophysiological process, which has not been fully elucidated. The role of the second isolated retinal artery in retinal branch vein occlusion (BRVO) is rarely reported. This study evaluated the role of the second isolated retinal artery in retinal branch vein occlusion. Methods: one hundred and thirty patients (260 eyes) were randomly selected from the first affiliated Hospital of Dalian Medical University from March 2008 to October 2009, including 65 eyes (130 eyes) with BRVO and 65 eyes (130 eyes) with other non-vascular fundus disease. Color fundus photography and fluorescein angiography (FFA) were performed in 65 eyes of BRVO, 2 eyes of contralateral eye (healthy eye) and 3 eyes of other non-vascular fundus disease. 65 BRVO eyes in group 1 were divided into group a and group b according to the presence or absence of the "second isolated retinal artery". The second isolated retinal artery was recorded in each group. The visual acuity of group a and group b were recorded for 1 week, 1 month, 3 months and 6 months, respectively. Results: (1) there was no significant difference in the number of "second isolated retinal arteries" between BRVO eyes (8 / 65, 12%) and contralateral eyes (14 / 65, 22%), 蠂 2 = 1.96 (P 0.05). The number of "second isolated retinal arteries" in BRVO eyes (8 / 65 / 12%) was significantly higher than that in other non-vascular fundus diseases (44 / 130 / 34%). In BRVO group, there was significant difference in the first diagnosis visual acuity between group a and group b with or without "the second isolated retinal artery" (P0.05). The visual acuity of 1 week, 1 month, 3 months and 6 months were also compared, the difference was statistically significant (P0.05). Conclusion: "the second isolated retinal artery" may reduce the number of retinal arteriovenous crossover and decrease the incidence of BRVO, and indirectly improve the visual acuity of BRVO eyes, but can protect the prognosis of BRVO eyes.
【学位授予单位】：大连医科大学
【学位级别】：硕士
【学位授予年份】：2010
【分类号】：R774.1

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