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新生儿听力筛查和婴幼儿听神经病

发布时间:2018-11-25 09:16
【摘要】:目的:分析婴幼儿未通过听力筛查的原因及婴幼儿听神经病的临床听力学特征 方法:检测对象来自2009年5月—2010年2月广州及周边地区2次筛查未能通过或前后2次筛查结果不一致而转诊到我科进行听力学评估,少部分出生已通过当地妇幼保健院所作的听力筛查,但至4、5月龄,家长发现患儿对声音反应差,而到我院做听力学检测评估的6个月龄内的婴幼儿,共952例1882耳㖞,做听性脑干反应auditory brainstem response, ABR㖞、畸变产物耳声发射distortion product otoacoustic emissions, DPOAE㖞、鼓室声导抗和镫骨肌反射测试。 结果:无高危组听力筛查通过率高于高危因素组P0.05或P0.01㖞;无高危组听力损失低于高危因素组P0.05㖞;早产,极低体重,新生儿窒息,宫内病毒感染,机械通气≥5天,≥2个高危因素的ABR反应阈值与无高危因素组之间的差异有显著性P0.05或P0.01㖞;多因素logistic回归分析发现早产,极低体重,耳聋家族史,颌面畸形,机械通气≥5天可作为听力损失的高危因素。其中11例婴幼儿因耳蜗和听神经反应分离DPOAE通过,ABR无反应㖞而诊断为听神经病 结论:新生儿听力筛查是一项长期艰巨的任务,对有高危因素的患儿应加强筛查力度,积极预防和治疗新生儿围产期高危影响因素,减少听力损失的发病率;耳声发射正常和听性脑干反应及其反应阈之间的严重不一致性,鼓室图正常,镫骨肌反射引不出是婴幼儿听神经病较为显著的临床听力学特征,可用于婴幼儿听神经病的早期诊断。
[Abstract]:Objective: to analyze the causes of hearing failure in infants and young children and the clinical audiological characteristics of auditory neuropathy in infants. Methods: the subjects from May 2009 to February 2010 in Guangzhou and the surrounding areas failed to pass the screening. Or two times after the screening results were inconsistent and referred to my department for audiology evaluation, A small number of births have passed the hearing screening conducted by the local maternal and child health care center, but by the age of 45 to 5 months, parents found that the children had a poor response to sound, while to the children within 6 months of age who were assessed by audiology in our hospital, a total of 952 cases? 1882 ears? Auditory brainstem response? auditory brainstem response, ABR?, distortion product otoacoustic emission? distortion product otoacoustic emissions, DPOAE?, tympanic acoustic impedance and stapes reflex. Results: the passing rate of hearing screening in non-high risk group was higher than that in high risk factor group (P0.05 or P0.01), and the hearing loss in non-high risk group was lower than that in high risk factor group (P0.05). The ABR response threshold of premature delivery, very low body weight, neonatal asphyxia, intrauterine virus infection, mechanical ventilation 鈮,

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