甲硫氨酸片对噪声性听力损伤的保护作用
发布时间:2018-12-08 16:17
【摘要】:目的:探讨口服甲硫氨酸片对噪声性听力损伤的预防作用。方法:选择某部健康男性军人203人作为受试者,随机分为实验组(113例)和对照组(90例),噪声暴露前两组分别给予口服甲硫氨酸片和安慰剂1 500mg/d×3d。两组受试者噪声暴露前、后均行纯音测听和ABR检查,对检查结果进行统计学分析。结果:噪声暴露前纯音听阈、ABR波Ⅰ~Ⅴ间期在两组之间无显著差异(P0.05),但两组之间在噪声暴露后1d、7d均存在显著差异(分别P0.01和P0.05);与各自噪声暴露前比较,纯音听阈、ABR波Ⅰ~Ⅴ间期,噪声暴露后1d实验组、对照组均存在显著差异(分别P0.05和P0.01);噪声暴露后7d实验组无显著性差异(P0.05),对照组差异有统计学意义(P0.05)。结论:噪声暴露前口服甲硫氨酸片可减轻噪声性听力损伤,但最佳使用时机还需进一步研究。
[Abstract]:Objective: to investigate the preventive effect of oral methionine tablets on noise-induced hearing impairment. Methods: a total of 203 healthy male soldiers were randomly divided into experimental group (113 cases) and control group (90 cases). Before noise exposure, the two groups were given oral methionine tablets and placebo 1 500mg/d 脳 3 d, respectively. Before and after noise exposure, pure tone audiometry and ABR were performed in both groups. Results: before noise exposure, there was no significant difference in pure tone hearing threshold and ABR wave 鈪,
本文编号:2368635
[Abstract]:Objective: to investigate the preventive effect of oral methionine tablets on noise-induced hearing impairment. Methods: a total of 203 healthy male soldiers were randomly divided into experimental group (113 cases) and control group (90 cases). Before noise exposure, the two groups were given oral methionine tablets and placebo 1 500mg/d 脳 3 d, respectively. Before and after noise exposure, pure tone audiometry and ABR were performed in both groups. Results: before noise exposure, there was no significant difference in pure tone hearing threshold and ABR wave 鈪,
本文编号:2368635
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