刺激声间隔觉察阈测试在听神经病患者诊断中的临床应用
发布时间：2018-12-15 15:04
【摘要】：目的建立刺激声间隔觉察测试(Random Gap Detection Test,RGDT)方法并对健听青年人、感音性聋患者及听神经病患者的听觉间隔觉察阈(Gaps-in-Noise,GIN)进行比较和分析。方法本文主要通过在噪声下改变间隔时间的长短来检测受试者听觉系统的时间整合能力。噪声间隔的改变采用的是一种自适应的调节方式,即连续两次选择正确则增加测试难度,缩短间隔时间;若一次选择错误则降低测试难度,延长间隔时间。本文选取健听组60耳,感音性耳聋组25耳,听神经病组20耳,分别进行GIN测试。结果健听组中,女性的GIN阈值为2.95±0.86ms,男性的GIN阈值为3.10±1.15ms,男女性别无显著性差异(P=0.6830.05,F=0.138);双耳的测试结果为3.02±1.00ms,左耳的测试结果为3.63±1.39ms,右耳的测试结果为3.38±1.25ms,不同耳别之间没有显著性差异(P=0.1620.05,F=1.857)。用one-way ANOVA对听神经病组、感音性聋组及健听组进行统计学分析发现三组有显著性差异(P=0.0000.05),其中听神经病组GIN阈值为29.59±19.27ms,与健听组3.34±1.24ms相比明显延长(P=0.0000.05),感音性聋组5.34±2.78ms与健听组有显著性差异(P=0.0050.05),听神经病组与感音性聋组相比也有显著性差异(P=0.0000.05)。结论 RG-DT是一种测试听觉中枢系统时间分辨率的一项有效方法,可行性高,尤其对于听神经病患者的临床应用价值较高。RGDT可以为进一步鉴别诊断听神经病和感音性聋提供一定参考依据。间隔觉察阈值测试可作为一项辅助工具补充并验证言语测听的测试结果。
[Abstract]:Objective to establish the method of stimulating acoustic interval awareness test (Random Gap Detection Test,RGDT) and to compare and analyze the auditory interval perception threshold (Gaps-in-Noise,GIN) in healthy young people, patients with sensorineural hearing loss and patients with auditory neuropathy. Methods the temporal integration ability of the auditory system was measured by changing the interval under noise. The change of noise interval adopts an adaptive adjustment method, that is, the correct choice of two consecutive times increases the test difficulty, shortens the interval time, and reduces the test difficulty and prolongs the interval time if one selection error is made. 60 ears of healthy hearing group, 25 ears of sensorineural deafness group and 20 ears of auditory neuropathy group were tested by GIN. Results in the healthy hearing group, the GIN threshold of female was 2.95 卤0.86msand that of male was 3.10 卤1.15ms.There was no significant difference between male and female (P < 0.6830.05F = 0.138). The test results of binaural, left and right ears were 3.02 卤1.00ms, 3.63 卤1.39ms and 3.38 卤1.25msrespectively. There was no significant difference between the two ears (P < 0.1620.05). The statistical analysis of auditory neuropathy group, sensorineural deafness group and healthy hearing group by one-way ANOVA showed that there were significant differences among the three groups (P0. 0000. 05). The GIN threshold of auditory neuropathy group was 29. 59 卤19. 27ms. Compared with the healthy hearing group (3.34 卤1.24ms), the hearing loss group (5.34 卤2.78ms) was significantly longer than that of the healthy hearing group (P0. 005. 05), and there was a significant difference between the sensorineural hearing loss group (5. 34 卤2.78ms) and the healthy hearing group (P0. 005. There was also significant difference between auditory neuropathy group and sensorineural deafness group (P = 0.0000.05). Conclusion RG-DT is an effective method for measuring the temporal resolution of auditory central system. Especially for the patients with auditory neuropathy, RGDT can provide some references for the further differential diagnosis of auditory neuropathy and sensorineural deafness. Interval awareness threshold test can be used as an auxiliary tool to supplement and verify the results of speech audiometry.
【作者单位】： 解放军总医院耳鼻咽喉头颈外科-耳内科解放军耳鼻咽喉研究所;解放军总医院耳鼻咽喉头颈外科—耳内科解放军耳鼻咽喉研究所;
【基金】：国家重大科学研究计划项目(2014CB943001) 国家自然基金重大国际合作项目(81120108009) 全军“十二五”重点项目(BWS11J026)联合资助
【分类号】：R764
[Abstract]:Objective to establish the method of stimulating acoustic interval awareness test (Random Gap Detection Test,RGDT) and to compare and analyze the auditory interval perception threshold (Gaps-in-Noise,GIN) in healthy young people, patients with sensorineural hearing loss and patients with auditory neuropathy. Methods the temporal integration ability of the auditory system was measured by changing the interval under noise. The change of noise interval adopts an adaptive adjustment method, that is, the correct choice of two consecutive times increases the test difficulty, shortens the interval time, and reduces the test difficulty and prolongs the interval time if one selection error is made. 60 ears of healthy hearing group, 25 ears of sensorineural deafness group and 20 ears of auditory neuropathy group were tested by GIN. Results in the healthy hearing group, the GIN threshold of female was 2.95 卤0.86msand that of male was 3.10 卤1.15ms.There was no significant difference between male and female (P < 0.6830.05F = 0.138). The test results of binaural, left and right ears were 3.02 卤1.00ms, 3.63 卤1.39ms and 3.38 卤1.25msrespectively. There was no significant difference between the two ears (P < 0.1620.05). The statistical analysis of auditory neuropathy group, sensorineural deafness group and healthy hearing group by one-way ANOVA showed that there were significant differences among the three groups (P0. 0000. 05). The GIN threshold of auditory neuropathy group was 29. 59 卤19. 27ms. Compared with the healthy hearing group (3.34 卤1.24ms), the hearing loss group (5.34 卤2.78ms) was significantly longer than that of the healthy hearing group (P0. 005. 05), and there was a significant difference between the sensorineural hearing loss group (5. 34 卤2.78ms) and the healthy hearing group (P0. 005. There was also significant difference between auditory neuropathy group and sensorineural deafness group (P = 0.0000.05). Conclusion RG-DT is an effective method for measuring the temporal resolution of auditory central system. Especially for the patients with auditory neuropathy, RGDT can provide some references for the further differential diagnosis of auditory neuropathy and sensorineural deafness. Interval awareness threshold test can be used as an auxiliary tool to supplement and verify the results of speech audiometry.
【作者单位】： 解放军总医院耳鼻咽喉头颈外科-耳内科解放军耳鼻咽喉研究所;解放军总医院耳鼻咽喉头颈外科—耳内科解放军耳鼻咽喉研究所;
【基金】：国家重大科学研究计划项目(2014CB943001) 国家自然基金重大国际合作项目(81120108009) 全军“十二五”重点项目(BWS11J026)联合资助
【分类号】：R764
【参考文献】
相关期刊论文 前9条
1 王秋菊;;听神经病的临床及基础研究[J];国际耳鼻咽喉头颈外科杂志;2006年06期
2 马丽涛;李娜;孙R，
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