等离子射频消融手术对早期声门型喉癌的疗效
发布时间：2019-03-09 08:45
【摘要】：目的：回顾性分析等离子射频消融手术对早期声门型喉癌的治疗效果。 方法：2009年11月—2014年1月，在上海交通大学附属上海市第六人民医院耳鼻咽喉头颈外科收治的早期声门型喉癌患者53例。其中行等离子射频消融术患者15例，行CO2激光切除术患者13例，行部分喉切除术患者25例。所有患者术后门诊电子喉镜及电话随访。应用SPSS18.0统计分析比较三种手术方案的临床数据。 结果：早期声门型喉癌患者经等离子射频治疗后平均住院天数为（8.20±2.76）天， CO2激光治疗后为（9.23±4.02）天（P=0.431），，部分喉切除治疗后为（19.68±10.14）天（P=0.000及0.001）;等离子射频治疗组平均手术时间为（0.92±0.65）h，CO2激光治疗组为（0.72±0.34）h（P=0.320），而部分喉切除治疗为（2.61±0.92）h（P=0.000及0.000）;CO2激光治疗组住院费用优于等离子射频治疗组（P=0.043），两者明显优于部分喉切除组；等离子射频组及CO2激光组术中出血明显优于部分喉切除组；三组术后复发率无明显统计学差异。 结论：等离子射频消融治疗早期声门型喉癌的术后复发率，相对于CO2激光治疗和部分喉切除治疗无明显差异；较部分喉切除手术具有手术时间短、创伤小、无需气管切开、术后并发症少、术后生活质量高等优势。
[Abstract]:Objective: to retrospectively analyze the therapeutic effect of plasma radiofrequency ablation for early glottic carcinoma. Methods: from November 2009 to January 2014, 53 patients with early glottic laryngeal carcinoma were treated in the department of otorhinolaryngology, head and neck surgery, Shanghai sixth people's Hospital affiliated to Shanghai Jiaotong University. Plasma radiofrequency ablation was performed in 15 cases, CO2 laser in 13 cases, and partial laryngectomy in 25 cases. All patients were followed up by electronic laryngoscope and telephone. SPSS18.0 was used to analyze and compare the clinical data of three surgical schemes. Results: the average hospitalization days of patients with early glottic carcinoma and CO2 laser were (8.20 卤2.76) days and (9.23 卤4.02) days (P = 0.431), and the mean hospitalization days after plasma radio frequency treatment were (8.20 卤2.76) days and (9.23 卤4.02) days, respectively. After partial laryngectomy, it was (19.68 卤10.14) days (P < 0.0000 and 0.001). The mean operating time was (0.92 卤0.65) h in the plasma radio frequency group, (0.72 卤0.34) h (/ P / L) in the CO _ 2 laser group, and (2.61 卤0.92) h (/ L) in the partial laryngectomy group (P < 0.05 and 0.000). The hospitalization cost of CO2 laser treatment group was better than that of plasma radio frequency treatment group (P0. 043), and both of them were significantly better than partial laryngectomy group. The bleeding in plasma radio frequency group and CO2 laser group was significantly better than that in partial laryngectomy group, and there was no significant difference in postoperative recurrence rate among the three groups. Conclusion: the recurrence rate of early glottic carcinoma treated with plasma radiofrequency ablation has no significant difference compared with CO2 laser and partial laryngectomy. Compared with partial laryngectomy, it has the advantages of shorter operation time, less trauma, no tracheotomy, less complications and higher quality of life after operation.
【学位授予单位】：上海交通大学
【学位级别】：硕士
【学位授予年份】：2014
【分类号】：R739.65
[Abstract]:Objective: to retrospectively analyze the therapeutic effect of plasma radiofrequency ablation for early glottic carcinoma. Methods: from November 2009 to January 2014, 53 patients with early glottic laryngeal carcinoma were treated in the department of otorhinolaryngology, head and neck surgery, Shanghai sixth people's Hospital affiliated to Shanghai Jiaotong University. Plasma radiofrequency ablation was performed in 15 cases, CO2 laser in 13 cases, and partial laryngectomy in 25 cases. All patients were followed up by electronic laryngoscope and telephone. SPSS18.0 was used to analyze and compare the clinical data of three surgical schemes. Results: the average hospitalization days of patients with early glottic carcinoma and CO2 laser were (8.20 卤2.76) days and (9.23 卤4.02) days (P = 0.431), and the mean hospitalization days after plasma radio frequency treatment were (8.20 卤2.76) days and (9.23 卤4.02) days, respectively. After partial laryngectomy, it was (19.68 卤10.14) days (P < 0.0000 and 0.001). The mean operating time was (0.92 卤0.65) h in the plasma radio frequency group, (0.72 卤0.34) h (/ P / L) in the CO _ 2 laser group, and (2.61 卤0.92) h (/ L) in the partial laryngectomy group (P < 0.05 and 0.000). The hospitalization cost of CO2 laser treatment group was better than that of plasma radio frequency treatment group (P0. 043), and both of them were significantly better than partial laryngectomy group. The bleeding in plasma radio frequency group and CO2 laser group was significantly better than that in partial laryngectomy group, and there was no significant difference in postoperative recurrence rate among the three groups. Conclusion: the recurrence rate of early glottic carcinoma treated with plasma radiofrequency ablation has no significant difference compared with CO2 laser and partial laryngectomy. Compared with partial laryngectomy, it has the advantages of shorter operation time, less trauma, no tracheotomy, less complications and higher quality of life after operation.
【学位授予单位】：上海交通大学
【学位级别】：硕士
【学位授予年份】：2014
【分类号】：R739.65
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