激光配合中药治疗糖尿病视网膜病变（DR）的临床研究

发布时间：2019-03-13 21:29

【摘要】： 目的:观察研究激光配合中药(活血化淤,益气养阴兼以利水)治疗糖尿病视网膜病变的临床疗效。方法:选2008年1月到2010年2月于吉林省中医院(长春中医药大学附属医院)眼科门诊及疗区住院的糖尿病性视网膜病变患者50例(78眼),其中29例患者双眼符合入选标准,21例患者单眼符合入选条件。将29例双眼符合入选标准的患者,按随机分配的方式分配到治疗组15例(30眼),对照组14例(28眼);将21例(21眼)单眼符合入选标准的患者,按随机分配的方式选分配到治疗组11例(11眼),对照组10例(10眼)。治疗组25例(40眼)应用激光配合中药治疗,对照组25例(38眼)仅接受激光治疗,观察两组的临床有效率。入选患者均进行全面的眼科检查,治疗后各随访15天、30天,观察两组患者治疗前后视力、眼底改变及眼底血管造影结果的变化情况,分析两组治疗的效果,并做出相应的结论。结果:(1)治疗一个月后治疗组视网膜出血与渗出及微动脉瘤吸收的有效率是92.5%,对照组的有效率是77.8%;两组相比有统计学意义(P0.05);(2)治疗1个月后治疗组黄斑水肿消失的有效率是94.1%,对照组的有效率是71.4%;两组相比有统计学意义(P0.05);(3)治疗1个月后视力提高治疗组总有效率是82.5%,对照组总有效率是52.8%;两组组比较有统计学意义(P0.05)。结论:治疗组的疗效优于对照组,表现在治疗组治疗1个月时视网膜出血、渗出吸收的疗效显著优于对照组,治疗组治疗1个月时黄斑水肿吸收、微动脉瘤消失及视力提高的疗效显著优于对照组,表明中药配合激光治疗糖尿病视网膜病变具有一定优势。
[Abstract]:Aim: to observe and study the clinical effect of laser combined with traditional Chinese medicine (activating blood circulation and removing blood stasis, tonifying qi and nourishing yin combined with diuresis) in treating diabetic retinopathy. Methods: from January 2008 to February 2010, 50 patients (78 eyes) with diabetic retinopathy who were hospitalized in the ophthalmology clinic and treatment area of Jilin traditional Chinese Medicine Hospital (affiliated Hospital of Changchun University of traditional Chinese Medicine) were selected. One eye of 21 patients met the selection criteria. Twenty-nine patients who met the criteria were randomly assigned to 15 cases (30 eyes) in the treatment group and 14 cases (28 eyes) in the control group. Twenty-one patients (21 eyes) who met the criteria were randomly assigned to 11 patients (11 eyes) in the treatment group and 10 eyes (10 eyes) in the control group. Twenty-five patients (40 eyes) in the treatment group were treated with laser combined with traditional Chinese medicine, while 25 patients (38 eyes) in the control group were treated only with laser. The clinical effective rates of the two groups were observed. All the patients were followed up for 15 days and 30 days after the treatment. The visual acuity, fundus changes and fundus angiography were observed before and after treatment in two groups, and the therapeutic effects of the two groups were analyzed. And draw a corresponding conclusion. Results: (1) the effective rate of retinal hemorrhage, exudation and microaneurysm absorption was 92.5% in the treatment group and 77.8% in the control group after one month treatment, there was significant difference between the two groups (P0.05). (2) the effective rate of macular edema disappearance was 94.1% in the treatment group and 71.4% in the control group 1 month after treatment, there was significant difference between the two groups (P0.05). (3) 1 month after treatment, the total effective rate was 82.5% in the treatment group and 52.8% in the control group, and there was significant difference between the two groups (P0.05). Conclusion: the therapeutic effect of the treatment group is superior to that of the control group. The therapeutic effect of the treatment group on retinal hemorrhage and exudation absorption is significantly better than that of the control group. The macular edema absorption of the treatment group is one month after treatment. The disappearance of microaneurysms and the improvement of visual acuity were significantly better than those of the control group, which indicated that Chinese herbal medicine combined with laser therapy had some advantages in the treatment of diabetic retinopathy.
【学位授予单位】：长春中医药大学
【学位级别】：硕士
【学位授予年份】：2010
【分类号】：R587.2;R774.1

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