声诱发短潜伏期负电位（ASNR）在正常耳诱发之初探
发布时间：2019-04-17 16:59
【摘要】： 目的:ASNR为重度感音性聋耳在强声刺激下出现的诱发电位,在电生理学方面已验证其与VEMP同起源于球囊,而与听力和冰水试验结果无关,为脑干水平前庭源性电位。本研究拟通过对正常人耳进行噪声掩蔽,消除听觉成分(ABR波)的出现,在强声刺激下诱发出现短潜伏期负电位ASNR。 方法:对20个正常人(志愿者)分别进行气导VEMP短声刺激,记录下VEMP的出现率、潜伏期,再测试掩蔽后的VEMP出现率;进行气导ABR测试,记录ABR波,再通过气导强声刺激,骨导噪声掩蔽,诱发ASNR波出现,探讨ASNR波的出现率、潜伏期。 结果:20个正常人(40耳)中12耳出现ASNR,出现率为30%,其阈值范围为85-105dB nHL,平均为97.5±5.24 dB nHL,掩蔽噪声阈值范围为70-90dB nHL ,平均为81.67±7.53dB nHL,潜伏期范围2.72-3.36ms(平均为3.11±0.15ms),阈值平均潜伏期3.02±0.16ms。做VEMP测试时,气导短声刺激加骨导噪声掩蔽40耳有19耳诱发出p13和n23波,出现率为47.5%,其p13潜伏期范围为11.92-14.15ms,平均为12.81±0.83ms,n23潜伏期范围18.98-22.19ms,平均为20.52±0.89ms。 结论:根据ASNR波的出现依赖于正常的球囊功能,在重度感音神经性聋患者中,ASNR的出现已经被证实。本实验应用骨导耳机发出噪声掩蔽模拟感音神经性聋,由气导耳机高强度声刺激成功诱发出ASNR波形。证明ASNR不仅出现在重度耳聋的患者,在正常人耳中同样可以引出。
[Abstract]:Aim: ASNR is a kind of evoked potential of severe sensorineural deafness under intense sound stimulation. It has been proved in electrophysiology that it originated from balloon with VEMP, but not with the results of hearing and ice water test. It is a vestibular potential at brainstem level. The aim of this study is to eliminate the appearance of auditory components (ABR wave) by noise masking in normal human ears, and to induce short latency negative potentials (ASNR.) under intense sound stimulation. Methods: 20 normal subjects (volunteers) were subjected to short sound stimulation with air conduction VEMP. The occurrence rate and latency of VEMP were recorded, and then the VEMP occurrence rate after masking was tested. The ABR wave was recorded by ABR test, and then the occurrence rate and latency of ASNR wave were discussed. The ASNR wave was induced by strong acoustic stimulation, bone conduction noise masking, and the occurrence rate and latency of ASNR wave were discussed. Results: the occurrence rate of ASNR, was 30% in 12 ears of 20 normal subjects (40 ears). The threshold range of 85-105dB nHL, was 97.5 卤5.24 dB nHL, the masking noise threshold was 81.67 卤7.53dB nHL, in 70-90dB nHL,. The range of latency was 2.72-3.36ms (mean 3.11 卤0.15ms), and the mean threshold latency was 3.02 卤0.16ms. During the VEMP test, 19 ears (47.5%) induced p13 and n23 waves in 40 ears with air conduction short sound stimulation and bone conduction noise masking. The latency range of p13 was 11.92 卤14.15 Ms (average 12.81 卤0.83 Ms), and the latency range of p13 was 11.92 渭 14.15 Ms (mean, 12.81 卤0.83 Ms) in 19 ears (47.5%). The n23 incubation period ranged from 18.98 to 22.19 Ms, with an average of 20.52 卤0.89 Ms. Conclusion: according to the appearance of ASNR wave depends on the normal balloon function, the appearance of ASNR has been confirmed in patients with severe sensorineural deafness. In this study, bone-guided headphones were used to masking simulated sensorineural deafness, and ASNR waveforms were successfully induced by high-intensity acoustic stimulation of air-guided headphones. It is concluded that ASNR is not only present in patients with severe deafness, but also can be induced in normal human ears.
【学位授予单位】：广西医科大学
【学位级别】：硕士
【学位授予年份】：2010
【分类号】：R764
本文编号：2459621
[Abstract]:Aim: ASNR is a kind of evoked potential of severe sensorineural deafness under intense sound stimulation. It has been proved in electrophysiology that it originated from balloon with VEMP, but not with the results of hearing and ice water test. It is a vestibular potential at brainstem level. The aim of this study is to eliminate the appearance of auditory components (ABR wave) by noise masking in normal human ears, and to induce short latency negative potentials (ASNR.) under intense sound stimulation. Methods: 20 normal subjects (volunteers) were subjected to short sound stimulation with air conduction VEMP. The occurrence rate and latency of VEMP were recorded, and then the VEMP occurrence rate after masking was tested. The ABR wave was recorded by ABR test, and then the occurrence rate and latency of ASNR wave were discussed. The ASNR wave was induced by strong acoustic stimulation, bone conduction noise masking, and the occurrence rate and latency of ASNR wave were discussed. Results: the occurrence rate of ASNR, was 30% in 12 ears of 20 normal subjects (40 ears). The threshold range of 85-105dB nHL, was 97.5 卤5.24 dB nHL, the masking noise threshold was 81.67 卤7.53dB nHL, in 70-90dB nHL,. The range of latency was 2.72-3.36ms (mean 3.11 卤0.15ms), and the mean threshold latency was 3.02 卤0.16ms. During the VEMP test, 19 ears (47.5%) induced p13 and n23 waves in 40 ears with air conduction short sound stimulation and bone conduction noise masking. The latency range of p13 was 11.92 卤14.15 Ms (average 12.81 卤0.83 Ms), and the latency range of p13 was 11.92 渭 14.15 Ms (mean, 12.81 卤0.83 Ms) in 19 ears (47.5%). The n23 incubation period ranged from 18.98 to 22.19 Ms, with an average of 20.52 卤0.89 Ms. Conclusion: according to the appearance of ASNR wave depends on the normal balloon function, the appearance of ASNR has been confirmed in patients with severe sensorineural deafness. In this study, bone-guided headphones were used to masking simulated sensorineural deafness, and ASNR waveforms were successfully induced by high-intensity acoustic stimulation of air-guided headphones. It is concluded that ASNR is not only present in patients with severe deafness, but also can be induced in normal human ears.
【学位授予单位】：广西医科大学
【学位级别】：硕士
【学位授予年份】：2010
【分类号】：R764
【参考文献】
相关期刊论文 前1条
1 兰兰;于黎明;陈之慧;郭明丽;赵建东;周娜;王秋菊;;短潜伏期负反应诊断前庭水管扩大的意义[J];听力学及言语疾病杂志;2006年04期
，本文编号：2459621
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