应用便携式多导睡眠监测仪对边远地区慢性心力衰竭伴睡眠呼吸暂停患者的临床意义

发布时间：2019-04-29 18:13

【摘要】：目的:应用便携式多导睡眠监测仪(PSG)监测边远地区慢性心力衰竭患者,分析其中睡眠呼吸暂停特别是中枢性睡眠呼吸暂停的临床意义。方法:选择云南省怒江傈僳族自治州人民医院心血管病内科住院的患者40例,应用PSG监测其中瓣膜性心脏病患者16例,其他病因引起的心脏扩大患者24例。根据呼吸暂停低通气指数(AHI)分为两组,即AHI≥5次/h组20例和AHI5次/h组20例,分析比较两组患者中枢性睡眠呼吸暂停与心功能的关系。结果:(1)AHI≥5次/h组患者美国纽约心脏协会(NYHA)心功能Ⅲ/Ⅳ级比例、左心房内径、左心室舒张末期内径、左心室收缩末期内径、左心室舒张末期容积、左心室收缩末期容积、AHI以及氧减指数均明显大于AHI5次/h组,而左心室射血分数低于AHI5次/h组,差异均有统计学意义(P均0.05)。(2)AHI≥5次/h组20例患者中以中枢性睡眠呼吸暂停为主16例,以阻塞性睡眠呼吸暂停为主4例。(3)多元Logistic向前逐步选择(Wald)回归分析结果表明,AHI≥5次/h与左心室射血分数[优势比(OR)=0.9,95%可信区间(CI):0.8~1.0,P=0.017)]、最低氧饱和度(OR=0.9,95%CI:0.7~1.0,P=0.022)以及左心室后壁厚度(OR=0.3,95%CI:0.1~0.9,P=0.034)相关;中枢性睡眠呼吸暂停与NYHA心功能Ⅲ/Ⅳ级相关(OR=15.0,95%CI:3.2~71.4,P=0.001)。结论:睡眠呼吸暂停尤其中枢性睡眠呼吸暂停是严重慢性心力衰竭的一种表现,PSG应用于边远地区慢性心力衰竭患者的评估及治疗随访,具有现实意义。
[Abstract]:Aim: to monitor chronic heart failure patients in remote areas by portable polysomnography (PSG), and to analyze the clinical significance of sleep apnea, especially central sleep apnea. Methods: forty patients in the Department of Cardiovascular Diseases of Nujiang Lisu Autonomous Prefecture people's Hospital in Yunnan Province were selected. PSG was used to monitor 16 patients with valvular heart disease and 24 patients with heart enlargement caused by other causes. According to the apnea hypopnea index (AHI), the patients were divided into two groups: AHI 鈮，

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