OCT检测视神经纤维层厚度与视野的相关性研究
发布时间：2019-06-05 19:05
【摘要】： 目的:研究第三代光学相干断层扫描仪( stratus optical coherence tomography 3000,OCT3 )检测原发性开角型青光眼(primary open angle glaucoma,POAG)视神经纤维层( retinal nerve fiber layer,RNFL)厚度的改变和与OCULUS Easyflied视野计检测的视野平均缺损(mean defect,MD)的相关性,评估OCT3检测视神经纤维层厚度在POAG早期诊断中的价值。方法:34例( 68眼)正常人、37例(68眼)可疑开角型青光眼(SOAG)、37例(68眼)原发性开角型青光眼(POAG) ,采用OCULUS Easyflied视野计和OCT3分别进行视野平均缺损和视神经纤维层厚度的检测。比较OCT3检测三组间视神经纤维层厚度的差异,分析原发性开角型青光眼组自动视野计检测的视野平均缺损(MD)与OCT3检测的视神经纤维层厚度(RNFL)的关系。结果:OCT3检测正常组、SOAG组、POAG组三组中的任意两组的视神经纤维层厚度,除正常组与原发性可疑型青光眼组的Tavg无显著性差异(P=0.072)外,余三组间两两比较各值均存在显著性差异( P 0.05)。在原发性开角型青光眼组, Avg. Thi、Iavg和Savg与MD的相关性较好( P 0.01),Tavg与MD的相关性次之(P=0.010),Navg与MD的相关性较差(P=0.052)。结论:OCT3能够检测到青光眼早期的视神经纤维层厚度的改变,且与MD有基本一致的较好相关性。OCT3检测视神经纤维层厚度可用于POAG的早期诊断。
[Abstract]:Objective: to study the detection of optic nerve fiber layer (retinal nerve fiber layer, in primary open angle glaucoma (primary open angle glaucoma,POAG) by the third generation optical coherence tomography (stratus optical coherence tomography 3000, Oct 3). The correlation between the change of RNFL) thickness and the average visual field defect (mean defect,MD) detected by OCULUS Easyflied myometer was used to evaluate the value of OCT3 in the early diagnosis of POAG. Methods: 34 cases (68 eyes) of normal subjects, 37 cases (68 eyes) of suspected open angle glaucoma (SOAG), (68 eyes), 37 cases (68 eyes) of primary open angle glaucoma (POAG), OCULUS Easyflied optic field meter and OCT3 were used to detect the average visual field defect and optic nerve fiber layer thickness, respectively. To compare the difference of optic nerve fiber layer thickness among the three groups by OCT3, and to analyze the relationship between the average visual field defect (MD) detected by automatic visual field meter and the optic nerve fiber layer thickness (RNFL) measured by OCT3 in primary open angle glaucoma group. Results: the thickness of optic nerve fiber layer was measured by OCT3 in any two groups in normal group, SOAG group and POAG group, except that there was no significant difference in Tavg between normal group and primary suspected glaucoma group (P 鈮，
本文编号：2493756
[Abstract]:Objective: to study the detection of optic nerve fiber layer (retinal nerve fiber layer, in primary open angle glaucoma (primary open angle glaucoma,POAG) by the third generation optical coherence tomography (stratus optical coherence tomography 3000, Oct 3). The correlation between the change of RNFL) thickness and the average visual field defect (mean defect,MD) detected by OCULUS Easyflied myometer was used to evaluate the value of OCT3 in the early diagnosis of POAG. Methods: 34 cases (68 eyes) of normal subjects, 37 cases (68 eyes) of suspected open angle glaucoma (SOAG), (68 eyes), 37 cases (68 eyes) of primary open angle glaucoma (POAG), OCULUS Easyflied optic field meter and OCT3 were used to detect the average visual field defect and optic nerve fiber layer thickness, respectively. To compare the difference of optic nerve fiber layer thickness among the three groups by OCT3, and to analyze the relationship between the average visual field defect (MD) detected by automatic visual field meter and the optic nerve fiber layer thickness (RNFL) measured by OCT3 in primary open angle glaucoma group. Results: the thickness of optic nerve fiber layer was measured by OCT3 in any two groups in normal group, SOAG group and POAG group, except that there was no significant difference in Tavg between normal group and primary suspected glaucoma group (P 鈮，
本文编号：2493756
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