纳吸棉联合布地奈德混悬液在内镜鼻窦术后填塞中的应用

发布时间：2019-07-03 17:59

【摘要】：目的:探讨鼻内镜术后纳吸棉联合布地奈德混悬液填塞术腔的临床效果。方法:随机选取30例行双侧鼻窦内镜手术且完成随访的CRSwNP和CRSsNP患者,分为实验组(左侧鼻腔)和对照组(右侧鼻腔)。实验组在手术结束时用含有布地奈德混悬液的纳吸棉填塞术腔,对照组则单纯使用纳吸棉填塞术腔,分别在术后第2周、第1个月、第3个月时对患者行VAS评分及Lund-Kennedy内镜黏膜形态评分。结果:12组术后第2周、第1、3个月时患者整体不适感及鼻塞、鼻腔分泌物、头痛或头昏、鼻面部胀痛四大主观症状的VAS评分差异均有统计学意义(P0.05),实验组优于对照组。22组术后第2周、第1、3个月Lund-Kennedy内镜黏膜形态评分各项目得分及总分差异均有统计学意义(P0.05),实验组优于对照组;术后第1、3个月时,实验组的鼻腔阻力小于对照组(P0.05)。3术后第3个月,实验组28例(93.3%)病情完全控制,总有效率96.6%;对照组22例(73.3%)病情完全控制,总有效率93.3%。2组间病情完全控制率比较差异有统计学意义(P0.05);2组间总有效率比较差异无统计学意义(P0.05)。结论:鼻内镜术后应用含有布地奈德混悬液的纳吸棉填塞术腔,可明显改善患者术后的不适症状,促进黏膜的顺利转归,提高了病情完全控制率。
[Abstract]:Objective: to investigate the clinical effect of cotton aspiration combined with budesonide suspension filling cavity after endoscopic sinus surgery. Methods: 30 patients with CRSwNP and CRSsNP who underwent bilateral endoscopic sinus surgery were randomly divided into experimental group (left nasal cavity) and control group (right nasal cavity). At the end of the operation, the experimental group was filled with nalyl cotton with budesonide suspension, while the control group was treated with nalyl cotton tamponade alone. VAS score and Lund-Kennedy endoscopic mucous membrane morphology score were performed at the 2nd week, the first month and the third month after operation, respectively. Results: at the 2nd week, 1st and 3rd month after operation, there were significant differences in VAS scores of nasal congestion, nasal secretions, headache or dizziness and nasal and facial distension and pain in the 12 groups, and the experimental group was better than the control group. The scores and total scores of Lund-Kennedy endoscopic mucous membrane morphology scores in 22 groups were significantly different at the 2nd week, 1st and 3rd months after operation (P 0.05). The experimental group was superior to the control group. At the 1st and 3rd month after operation, the nasal resistance of the experimental group was lower than that of the control group (P 0.05). 3 at the 3rd month after operation, 28 cases (93.3%) in the experimental group were completely controlled, the total effective rate was 96.6%, 22 cases in the control group (73.3%) were completely controlled, and the total effective rate was 93.3%. There was no significant difference in the total effective rate between the two groups (P 0.05). Conclusion: the application of cotton suction tamponade with budesonide suspension after nasal endoscopy can obviously improve the uncomfortable symptoms, promote the smooth prognosis of mucous membrane and improve the complete control rate of the disease.
【作者单位】：武汉大学人民医院耳鼻咽喉-头颈外科;黄石市中心医院;湖北理工学院附属医院耳鼻咽喉科;
【分类号】：R765.9

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