共焦显微镜观察长期佩戴角膜接触镜对中学生高度近视眼角膜形态及屈光状态的影响

发布时间：2019-07-19 20:24

【摘要】：目的共焦显微镜观察长期佩戴不同类型角膜接触镜对中学生高度近视眼角膜上皮形态及屈光状态的影响。方法选取西安某中学16~19岁中学生81例162眼进行临床随诊观察,均为双眼高度近视戴镜矫正。以不同类型矫正方法的自然状态分为三组:框架眼镜SP(28例56眼)组为实验对照组;软性角膜接触镜SCL组(24例48眼);高透氧性硬性角膜接触镜RGPCL组(29例58眼);共焦显微镜分别于戴镜后1月、6月、1年、3年观察患眼角膜上皮形态,同时记录其眼屈光度及眼轴长度变化情况。数据采用SPSS 19.0统计软件处理。结果 1两种角膜接触镜长期佩戴均存在角膜上皮细胞密度减低,上皮厚度变薄的情况,其中RGPCL戴镜半年后与同时间段SCL组存在显著统计学差异(P0.05);2框架眼镜及软性角膜接触镜组患者屈光度及眼轴显著增加,硬性角膜接触镜佩戴者屈光度及眼轴长度增加不明显,结果有显著差异(P0.05)。3硬性角膜接触镜佩戴半年后,眼球屈光度及眼轴控制效果显著(P0.05)。结论 1长期佩戴角膜接触镜会对角膜上皮形态产生一定影响,主要表现为角膜上皮密度降低,厚度变薄;2高透气性硬性角膜接触镜对角膜上皮形态影响较小,且可有效控制眼轴增长,对青春期近视发展有一定防治作用;3硬性角膜接触镜在佩戴半年后对屈光度的控制更为有效。
[Abstract]:Objective to observe the effect of long-term wearing of different types of corneal contact lenses on corneal epithelial morphology and refractive status in middle school students with high myopia. Methods 81 cases (162 eyes) of 16 years old middle school students in Xi'an were followed up. All of them were corrected by binocular high myopia. The patients were divided into three groups according to the natural state of different types of correction methods: frame glasses SP (28 cases 56 eyes) group, soft corneal contact lens SCL group (24 cases 48 eyes), hyperoxia hard corneal contact lens RGPCL group (29 cases 58 eyes), confocal microscope observed corneal epithelial morphology at 1 month, 6 months, 1 year and 3 years after wearing lens, and recorded the changes of eye diopter and axial length. The data were processed by SPSS 19.0 statistical software. Results 1 the density of corneal epithelial cells and the thickness of epithelial cells decreased and the thickness of epithelial cells became thinner in both kinds of corneal contact lenses for a long time, and there was significant difference between RGPCL group and SCL group at the same time after wearing the lens for half a year (P 0.05). 2 the diopter and axis of the patients with frame glasses and soft contact lenses increased significantly, but the diopter and axial length of the hard contact lenses did not increase significantly, the results were significantly different (P 0.05). 3 after wearing the hard corneal contact lenses for half a year, the control effect of eyeball diopter and eye axis was significant (P 0.05). Conclusion (1) wearing corneal contact lens for a long time will have some influence on corneal epithelial morphology, which is mainly manifested in the decrease of corneal epithelial density and thinning. (2) High breathable hard corneal contact lens has little effect on corneal epithelial morphology, and can effectively control the growth of eye axis, which can prevent and cure the development of adolescent myopia. (3) rigid corneal contact lens is more effective in the control of diopter after wearing for half a year.
【作者单位】：陕西省人民医院眼科;
【基金】：陕西省科技厅社会发展攻关计划(No.2012SF2-19);陕西省科技厅社会发展攻关计划(No.2013K12-17-02)~~
【分类号】：R778.11

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