我院121例药品不良反应报告分析

发布时间：2018-01-10 11:33

本文关键词：我院121例药品不良反应报告分析　出处：《海峡药学》2016年11期 　论文类型：期刊论文

【摘要】：目的了解我院药品不良反应(Adverse drug reaction,ADR)发生的规律、特点及相关因素,为临床合理用药提供参考。方法通过国家ADR监测网下载我院2014年1月1日~2015年12月31日上报国家ADR监测中心的ADR报告121例,从患者性别、年龄、药品种类、给药途径、ADR累计器官和(或)系统及其临床表现、报告人职业、ADR程度及转归等进行回顾性统计分析。结果 121例ADR报告中,患者年龄以45岁以上为主;女性比男性发生ADR的比例高;给药途径以静脉滴注为主;抗感染药物所占比例最高,报告例数为49例(占37.12%),中枢神经系统用药排第2位,报告例数为23例(占17.42%);临床表现以皮肤及其附件最常见,有80例,占31.13%。结论 ADR的发生有多方面因素,应加强ADR的报告与监测,以促进临床合理用药,减少ADR的发生。
[Abstract]:Objective to understand the adverse drug reactions (Adverse drug, reaction, ADR) the occurrence regularity, characteristics and related factors, and provide reference for clinical rational drug use. Methods 121 cases by the national ADR monitoring network download in our hospital in January 1, 2014 ~2015 year in December 31st submitted to the national ADR monitoring center of the ADR report, from the patient's gender, age, types of drugs, to the route of administration, ADR and (or) the cumulative organ system and its clinical manifestation, reporting person occupation, ADR degree and prognosis were analyzed retrospectively. Results 121 cases of ADR reports, the age of patients over 45 years of age; women have a high proportion of ADR than men; intravenous; resistance infection drugs accounted for the highest proportion, the number of reported cases of 49 cases (37.12%), central nervous system drugs ranked second, the number of reported cases for 23 cases (17.42%); the clinical manifestations of skin and its accessories are the most common, there are 80 cases, accounting for 31.13%. conclusion There are many factors in the occurrence of ADR. The report and monitoring of ADR should be strengthened so as to promote the rational use of clinical drugs and reduce the occurrence of ADR.

【作者单位】：福建上杭县医院药剂科;
【分类号】：R95
【正文快照】： 药品不良反应(Adverse drug reaction,ADR)是指合格药品在正常用法、用量下出现的与用药目的无关的有害反应[1]。ADR监测是加强药品监管,提高用药质量,保障公众用药安全的重要手段。笔者对福建省上杭县医院(以下简称“我院”)上报的121例ADR报告进行统计分析。 1 资料与方法

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