应用国际指南评价某院外科住院患者人血白蛋白临床使用情况

发布时间：2018-01-24 00:14

本文关键词： 人血白蛋白回顾性调查临床应用国际指南　出处：《中国药房》2016年29期 　论文类型：期刊论文

【摘要】：目的:为外科住院患者人血白蛋白临床合理使用提供参考。方法:分析某院外科2014年1-3月住院患者人血白蛋白的使用情况,并以美国大学医院联合会(UHC)制订的《人血白蛋白、非蛋白胶体及晶体溶液使用指南》(2010版)和欧洲《免疫球蛋白及白蛋白使用推荐》为标准进行评价。结果:556例患者共提交了895份人血白蛋白使用申请,主要集中在胃肠外科(29.7%)、肝胆外科(25.9%)和胸心外科(13.1%)。主要的用药理由为纠正低白蛋白血症(62.9%),其次是大手术期间的白蛋白补充(7.9%)和减轻肝硬化患者的腹水(4.4%);仅95份(10.6%)人血白蛋白申请理由符合指南适应证。最主要的不适宜用药理由为纠正低白蛋白血症。结论:该院外科住院患者人血白蛋白用量大,且其适应证与指南相符率低,需加强人血白蛋白的合理、规范使用。
[Abstract]:Objective: to provide a reference for the rational use of human serum albumin (HSA) in surgical inpatients. Methods: to analyze the use of human serum albumin (HSA) in inpatients in a hospital from 2014 to 2014. Human serum albumin (HSA) was developed by UHCA (American Federation of University Hospitals). Guide to the use of Nonprotein Colloids and Crystal Solutions. Results A total of 895 applications for the use of human serum albumin were submitted in 556 patients. It was mainly concentrated in Gastrointestinal surgery (29.7T), hepatobiliary surgery (25.9g) and Thoracic and Cardiac surgery (13.1g). The main reason for medication was to correct hypoalbuminemia (62.9%). The second was albumin supplement (7.9g) and ascitic fluid relief (4.4%) during major operation. Only 95 patients (10.6%) applied for human serum albumin (HSA) were in accordance with the indications of the guidelines. The most important reason for drug use was to correct hypoalbuminemia. Conclusion: the dosage of HSA in surgical inpatients in this hospital is large. And its indication is low in accordance with the guidelines, it is necessary to strengthen the rational use of human serum albumin.
【作者单位】：重庆医科大学附属第一医院药学部;
【分类号】：R977.8
【正文快照】： 人血白蛋白有维持血浆胶体渗透压、运输代谢物等功能。人血白蛋白作为由注射乙型肝炎疫苗免疫的健康人血浆或血清通过提取制成的制剂,在临床已经广泛使用超过70年。人血白蛋白原料的有限性决定了其供应量有限,所以随着临床需求的增加,时有供应短缺的情况发生,而且其昂贵的价格

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