我国2006-2015年肠外营养处方中维生素使用的文献分析

发布时间：2018-01-28 11:08

本文关键词： 营养支持治疗肠外营养维生素合理用药处方分析　出处：《中国药房》2017年17期 　论文类型：期刊论文

【摘要】：目的:了解我国肠外营养处方中维生素的使用情况,为我国肠外营养中维生素的合理使用提供参考。方法:以"肠外营养"或"静脉营养"和"处方分析"或"合理用药"或"医嘱分析"为关键词,检索中国知网和万方数据库中2006-2015年报道的有关肠外营养处方合理性分析文献,对纳入文献中维生素的使用情况进行分析和总结。结果:共纳入34篇文献,涉及的总处方数为158 874份,其中145 400份(91.52%)处方使用了维生素;有73 508份(46.27%)处方使用了12或13种维生素,53 388份(33.60%)处方被文献作者认为超量使用维生素,18 504份(11.65%)处方维生素添加不完全,1 663份(1.05%)处方未添加维生素。我国北部地区添加12或13种维生素的比例最高(52.00%)。"三甲"医院添加12或13种维生素、文献作者认为超量使用维生素和水溶性维生素、脂溶性维生素均未完全添加的比例均低于"三甲"以下医院。使用12或13种必需维生素比例由高到低的处方科室依次为肿瘤科(97.72%)、内科(86.62%)、重症监护病房(77.99%)和外科(52.83%)。结论:我国肠外营养处方中维生素规范使用的比例偏低,肠外营养中应添加符合推荐的多种维生素的观念仍需加强。
[Abstract]:Objective: to understand the use of vitamins in the prescription of parenteral nutrition in China. Methods: "parenteral nutrition" or "intravenous nutrition" and "prescription analysis" or "rational medication" or "doctor's order analysis" were used as the key words for the rational use of vitamins in parenteral nutrition in China. To search the literature on the rationality of parenteral nutrition prescription reported from 2006 to 2015 in China Zhiwang and Wanfang database. The use of vitamins in the literature was analyzed and summarized. Results: a total of 34 articles were included, involving a total of 158,874 prescriptions. Of these, 145,400 were prescribed with vitamins; There were 73,508 prescriptions using 12 or 13 vitamins, 53,388 or 33.60) prescriptions were considered overdose by the authors of the literature. (18,504) prescription vitamin supplements are incomplete. No vitamins were added to the prescription. The proportion of 12 or 13 vitamins added in the northern part of our country was the highest (52.00). ... the "three A" hospitals added 12 or 13 vitamins. The authors believe that excessive use of vitamins and water-soluble vitamins. The proportion of fat-soluble vitamins that were not completely added was lower than that of the hospitals below "three A". The prescription department with 12 or 13 essential vitamins from high to low was oncology department (97.72%). Conclusion: the proportion of the standard use of vitamins in the prescriptions of parenteral nutrition in China is on the low side. The idea that parenteral nutrition should be supplemented with recommended multivitamins still needs to be strengthened.
【作者单位】：国家癌症中心/中国医学科学院北京协和医学院肿瘤医院药剂科;北京京卫信康药物研究所;北京协和医院基本外科;
【基金】：国家重点研发计划课题(No.2016YFA0201504) 卫生计生委行业基金资助项目(No.201502022)
【分类号】：R977.2
【正文快照】： 肠外营养(Parenteral nutrition,PN)是将机体所需的葡萄糖、氨基酸、脂肪乳、电解质、维生素、微量元素等营养素按一定比例混合配制于营养袋中,形成全合一营养液,经静脉输注以供应患者所需要的营养物质。胃肠道功能部分或完全丧失、不能耐受肠内营养制剂的患者需应用PN支持,因

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