疏风解毒胶囊和磷酸奥司他韦胶囊治疗成人流感样症状的药物经济学评价

发布时间：2018-02-08 10:47

本文关键词： 流感样症状疏风解毒胶囊磷酸奥司他韦胶囊药物经济学评价成本效果分析　出处：《中国新药杂志》2017年01期 　论文类型：期刊论文

【摘要】：目的:评价疏风解毒胶囊和磷酸奥司他韦胶囊治疗成人流感样症状的经济性。方法:本研究采用前瞻性、实效临床试验设计方法,将流感样症状患者随机分为接受疏风解毒胶囊和磷酸奥司他韦胶囊治疗。由经过培训的调研员对患者进行随访,并收集成本和效果数据。以医疗卫生系统为研究角度,分别采用6个效果指标进行成本效果分析。结果:分别纳入接受疏风解毒胶囊和磷酸奥司他韦胶囊治疗的有效病例78例和72例。两组的48 h痊愈率(P=0.320)、48 h退热率(P=0.523)、48 h有效率(P=0.805)、5 d痊愈率(P=0.383)、5 d退热率(P=0.512)和5 d有效率(P=1.000)均无显著差异。疏风解毒胶囊组的门诊费用总额(P0.01)和药品费用(P0.01)显著低于磷酸奥司他韦胶囊组。结论:疏风解毒胶囊和磷酸奥司他韦胶囊治疗流感样症状的效果相当,疏风解毒胶囊成本低于磷酸奥司他韦胶囊,因此疏风解毒胶囊治疗流感样症状更具有经济性。
[Abstract]:Objective: to evaluate the economics of Shufeng jiedu capsule and oseltamivir phosphate capsule in the treatment of influenza like symptoms in adults. Patients with flu-like symptoms were randomly divided into two groups: Shufeng jiedu capsule and oseltamivir phosphate capsule. The patients were followed up by trained researchers, and cost and effect data were collected. Results: 78 cases and 72 cases were treated with Shufeng jiedu capsule and oseltamivir phosphate capsule respectively. There was no significant difference between the effective rate of 0. 805 and 5 days recovery rate and the antipyretic rate of 0. 383 and 5 days. The total outpatient expenses and drug cost of Shufeng jiedu capsule group were significantly lower than those of oseltamivir phosphate capsule group. Conclusion: the total outpatient expenses of Shufeng jiedu capsule group were significantly lower than that of oseltamivir phosphate capsule group (P 0. 01) and the effective rate of detoxification capsule group was lower than that of oseltamivir phosphate capsule group (P 0. 01). The effects of DU capsule and oseltamivir phosphate capsule on flu-like symptoms are comparable. The cost of Shufeng jiedu capsule is lower than oseltamivir phosphate capsule, so Shufeng jiedu capsule is more economical to treat influenza-like symptoms.
【作者单位】：中国药科大学国际医药商学院;上海市普陀区中心医院发热门诊;
【分类号】：R956

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