我院5770份肠外营养医嘱药物稳定性和选药合理性分析

发布时间：2018-02-10 06:17

本文关键词： 肠外营养处方点评临床诊断药物经济学稳定性　出处：《中国药房》2017年20期 　论文类型：期刊论文

【摘要】：目的:为肠外营养合理用药提供参考。方法:选取我院2015年5月-2016年4月5 770份肠外营养医嘱,结合患者营养状况、临床诊断和实验室检查,对其营养液的稳定性、选药合理性、药物经济性等进行综合分析。结果:5 770份肠外营养医嘱中,营养液稳定性合格率为89.46%;肝功能异常、肾功能异常、妊娠剧吐、胰腺炎、完全禁食、长期应用肠外营养(14 d)和三酰甘油4.5 mmol/L患者选药合理率分别为76.19%、63.16%、75.00%、78.95%、65.95%、64.06%和50.00%;作用相同、剂量相等、价格相差4~34倍的同类药物有4组,不合适选药率为7.58%~61.64%。结论:肠外营养处方设计时,既要考虑患者营养状况、临床诊断、实验室检查指标等个体情况,又要考虑药物高效、安全、经济及整个营养液稳定性。
[Abstract]:Objective: to provide reference for rational use of parenteral nutrition. Methods: from May 2015 to April 5th 2016, 770 prescriptions of parenteral nutrition in our hospital were selected, combined with the nutritional status of patients, clinical diagnosis and laboratory examination, the stability of nutrient solution was obtained. Results the qualified rate of nutrient solution stability was 89.46%, liver function abnormality, renal function abnormality, hyperemesis of pregnancy, pancreatitis, complete fasting, and so on, among 5 770 cases of parenteral nutrition doctor's orders, the qualified rate of nutrition solution was 89.46, abnormal liver function, abnormal renal function, hyperemesis of pregnancy, pancreatitis, complete fasting, and so on. The rational rate of drug selection for long-term application of parenteral nutrition for 14 days) and triglyceride 4.5 mmol/L patients were 76.19 and 75.00, 75.95% and 64.06%, respectively. There were 4 groups of the same drugs with the same effect, the same dosage and the price difference of 4 ~ 34 times, and the unsuitable drug selection rate was 7.58% 61.64.Conclusion: when the prescription of parenteral nutrition is designed, there are 4 groups of the same kind of drugs with the same effect and the same dosage, the price difference is 4%, and the unsuitable rate is 7.58% 61.644.Conclusion: when the prescription of parenteral nutrition is designed, We should not only consider the individual condition of patients' nutritional status, clinical diagnosis and laboratory examination, but also consider the drug efficiency, safety, economy and the stability of the whole nutrient solution.
【作者单位】：河北省人民医院营养科;河北省人民医院药学部;河北省人民医院医院感染控制科;
【基金】：河北省医学科学研究重点课题计划项目(No.20160466)
【分类号】：R95

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